日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD47 blockade-driven necroptosis complements BCL-2 inhibition-driven apoptosis in lymphoid malignancies.

CD47阻断驱动的坏死性凋亡可与BCL-2抑制驱动的淋巴恶性肿瘤细胞凋亡相辅相成。

Chong Stephen J F, Valentin Rebecca, Wang Jing, Zhu Fen, Gokhale Prafulla C, Eschle Benjamin K, Garbicz Filip, Iskandar Kartini, Sewastianik Tomasz, Toh Brienne C Y, Penailillo Johany, Peluso Marisa O, Zhang Jeremy, Hackett Liam, Collins Mary C, Lehmberg Timothy Z, Adam Ammar, Zhang Li, Armet Caroline M, Rausch Matthew, Lee Benjamin H, Holland Pamela M, Palombella Vito J, Paterson Alison M, Kong Li Ren, Ten Hacken Elisa, Guerriero Jennifer L, Herbaux Charles, Wu Catherine J, Chng Wee Joo, Pervaiz Shazib, Niemann Carsten U, Carrasco Ruben D, Davids Matthew S

Codon deoptimization of multispecific biologics reduces mispairing during transient mammalian protein expression

多特异性生物制剂的密码子去优化可减少瞬时哺乳动物蛋白表达过程中的错配。

Chang, Timothy Z; Ma, Weijun; Guo, Jane; Hu, Jiali; Mix, Kalie; Tang, Yi; Wong, Karen; Bric-Furlong, Eva; Lennon, Amanda; Hall, Brian; Hoffmann, Dietmar

BCL-2 dependence is a favorable predictive marker of response to therapy for chronic lymphocytic leukemia

BCL-2依赖性是慢性淋巴细胞白血病治疗反应的有利预测指标。

Chong, Stephen Jun Fei; Lu, Junyan; Valentin, Rebecca; Lehmberg, Timothy Z; Eu, Jie Qing; Wang, Jing; Zhu, Fen; Kong, Li Ren; Fernandes, Stacey M; Zhang, Jeremy; Herbaux, Charles; Goh, Boon Cher; Brown, Jennifer R; Niemann, Carsten U; Huber, Wolfgang; Zenz, Thorsten; Davids, Matthew S

Venetoclax plus dose-adjusted R-EPOCH for Richter syndrome

维奈托克联合剂量调整的R-EPOCH方案治疗里氏综合征

Davids, Matthew S; Rogers, Kerry A; Tyekucheva, Svitlana; Wang, Zixu; Pazienza, Samantha; Renner, Sarah K; Montegaard, Josie; Ihuoma, Udochukwu; Lehmberg, Timothy Z; Parry, Erin M; Wu, Catherine J; Jacobson, Caron A; Fisher, David C; Thompson, Philip A; Brown, Jennifer R

A T cell inflammatory phenotype is associated with autoimmune toxicity of the PI3K inhibitor duvelisib in chronic lymphocytic leukemia

AT细胞炎症表型与PI3K抑制剂duvelisib在慢性淋巴细胞白血病中的自身免疫毒性相关。

Deepti Gadi # ,Alec Griffith # ,Svitlana Tyekucheva ,Zixu Wang ,Vanessa Rai ,Alexander Vartanov ,Emily Thrash ,Stacey M Fernandes ,Timothy Z Lehmberg ,Brandon Lee ,Stephen P Martindale ,John-Hanson Machado ,Oreofe Odejide ,Philippe Armand ,David C Fisher ,Jon Arnason ,Matthew S Davids ,James A Lederer ,Jennifer R Brown

High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response

高内涵筛选和计算预测揭示抑制先天免疫反应的病毒基因

Tai L Ng, Erika J Olson, Tae Yeon Yoo, H Sloane Weiss, Yukiye Koide, Peter D Koch, Nathan J Rollins, Pia Mach, Tobias Meisinger, Trenton Bricken, Timothy Z Chang, Colin Molloy, Jérôme Zürcher, Roger L Chang, Timothy J Mitchison, John I Glass, Debora S Marks, Jeffrey C Way, Pamela A Silver

Theranostic cells: emerging clinical applications of synthetic biology

治疗诊断细胞:合成生物学的新兴临床应用

McNerney, Monica P; Doiron, Kailyn E; Ng, Tai L; Chang, Timothy Z; Silver, Pamela A

A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

纳米骡肽载体可将siRNA递送穿过完整的血脑屏障,从而减轻缺血性中风

Eyford, Brett A; Singh, Chaahat S B; Abraham, Thomas; Munro, Lonna; Choi, Kyung Bok; Hill, Tracy; Hildebrandt, Rhonda; Welch, Ian; Vitalis, Timothy Z; Gabathuler, Reinhard; Gordon, Jacob A; Adomat, Hans; Guns, Emma S T; Lu, Chieh-Ju; Pfeifer, Cheryl G; Tian, Mei Mei; Jefferies, Wilfred A

Corrigendum: A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

更正:纳米骡肽载体可将siRNA递送穿过完整的血脑屏障以减轻缺血性中风

Eyford, Brett A; Singh, Chaahat S B; Abraham, Thomas; Munro, Lonna; Choi, Kyung Bok; Hill, Tracy; Hildebrandt, Rhonda; Welch, Ian; Vitalis, Timothy Z; Gabathuler, Reinhard; Gordon, Jacob A; Adomat, Hans; Guns, Emma S T; Lu, Chieh-Ju; Pfeifer, Cheryl G; Tian, Mei Mei; Jefferies, Wilfred A

Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells

发现铁转运蛋白黑素转铁蛋白中高度保守的肽,该肽可穿过完整的血脑屏障并定位于神经细胞中

Chaahat S B Singh, Brett A Eyford, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Mark Okon, Timothy Z Vitalis, Reinhard Gabathuler, Chieh-Ju Lu, Cheryl G Pfeifer, Mei Mei Tian, Wilfred A Jefferies2