日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Serum Immune Profiling in Paediatric Crohn's Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict Clinical Response to Both Treatments

儿童克罗恩病血清免疫谱分析显示,一线英夫利昔单抗治疗比传统疗法具有更强的免疫调节作用,且治疗前免疫谱可预测两种疗法的临床疗效。

Jongsma, Maria M E; Costes, Lea M M; Tindemans, Irma; Cozijnsen, Martinus A; Raatgreep, Rolien H C; van Pieterson, Merel; Li, Yunlei; Escher, Johanna C; de Ridder, Lissy; Samsom, Janneke N

Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress.

Notch信号通路通过促进Th2细胞从淋巴结迁移而引发过敏性气道炎症

Tindemans Irma, van Schoonhoven Anne, KleinJan Alex, de Bruijn Marjolein Jw, Lukkes Melanie, van Nimwegen Menno, van den Branden Anouk, Bergen Ingrid M, Corneth Odilia Bj, van IJcken Wilfred Fj, Stadhouders Ralph, Hendriks Rudi W

International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study

一项旨在调查儿童期发病炎症性肠病疾病进程和异质性的国际前瞻性观察研究:PIBD-SETQuality初始队列研究方案

Aardoom, Martine A; Kemos, Polychronis; Tindemans, Irma; Aloi, Marina; Koletzko, Sibylle; Levine, Arie; Turner, Dan; Veereman, Gigi; Neyt, Mattias; Russell, Richard K; Walters, Thomas D; Ruemmele, Frank M; Samsom, Janneke N; Croft, Nicholas M; de Ridder, Lissy

The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma

Notch通路抑制剂——源自Mastermind样蛋白1 (SAHM1) 的α螺旋肽链——可消除过敏性哮喘的典型症状。

KleinJan, Alex; Tindemans, Irma; Montgomery, Jeffrey E; Lukkes, Melanie; de Bruijn, Marjolein J W; van Nimwegen, Menno; Bergen, Ingrid; Moellering, Raymond E; Hoogsteden, Henk C; Boon, Louis; Amsen, Derk; Hendriks, R W

T cells are necessary for ILC2 activation in house dust mite-induced allergic airway inflammation in mice

在小鼠尘螨诱发的过敏性呼吸道炎症中,T 细胞是 ILC2 激活所必需的

Bobby W S Li, Marjolein J W de Bruijn, Irma Tindemans, Melanie Lukkes, Alex KleinJan, Henk C Hoogsteden, Rudi W Hendriks