日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multispecies transcriptomics reveals influenza A virus modulation of Streptococcus pneumoniae EF3030 infection in human lung epithelium and murine lung

多物种转录组学揭示甲型流感病毒对人肺上皮细胞和鼠肺中肺炎链球菌EF3030感染的调控作用

D'Mello, Adonis; Earnhardt, Erin Y; Lane, Jessica R; Tipper, Jennifer L; Martínez, Eriel; Prokopczuk, Federico I; Im, Hansol; Roussey, Holly N; Harrod, Kevin S; Orihuela, Carlos J; Tettelin, Hervé

Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection

鼻内接种减毒活病毒载体SARS-CoV-2疫苗可诱导抗原特异性全身和黏膜免疫,并能抵抗病毒攻击和自然感染。

Botta, Davide; Schultz, Michael D; Silva-Sanchez, Aaron; Kalange, Davies; Akther, Jobaida; Zhou, Fen; Tipper, Jennifer L; Yang, Guang; Schaefers, Levi T; Barkley, Courtney A; Qiu, Shihong; Foote, Jeremy B; Tioni, Mariana F; Weiss, Christopher M; Phan, Shannon I; Green, Todd J; Leal, Sixto M Jr; Harrod, Kevin S; King, Rodney G; Moore, Martin L; Randall, Troy D; Tang, Roderick S; Lund, Frances E

ACE-2 blockade and TMPRSS2 inhibition mitigate SARS-CoV-2 severity following cigarette smoke exposure in airway epithelial cells in vitro.

ACE-2 阻断和 TMPRSS2 抑制可减轻体外气道上皮细胞暴露于香烟烟雾后 SARS-CoV-2 的严重程度

Hussain Shah S, Libby Emily Falk, Peabody Lever Jacelyn E, Tipper Jennifer L, Phillips Scott E, Mazur Marina, Li Qian, Campos-Gómez Javier, Harrod Kevin S, Rowe Steven M

Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge

单剂量鼻内给药AdCOVID可诱导针对SARS-CoV-2的全身性和黏膜免疫,并完全保护小鼠免受致命攻击。

King, R Glenn; Silva-Sanchez, Aaron; Peel, Jessica N; Botta, Davide; Dickson, Alexandria M; Pinto, Amelia K; Meza-Perez, Selene; Allie, S Rameeza; Schultz, Michael D; Liu, Mingyong; Bradley, John E; Qiu, Shihong; Yang, Guang; Zhou, Fen; Zumaquero, Esther; Simpler, Thomas S; Mousseau, Betty; Killian, John T Jr; Dean, Brittany; Shang, Qiao; Tipper, Jennifer L; Risley, Christopher A; Harrod, Kevin S; Feng, Tsungwei; Lee, Young; Shiberu, Bethlehem; Krishnan, Vyjayanthi; Peguillet, Isabelle; Zhang, Jianfeng; Green, Todd J; Randall, Troy D; Suschak, John J; Georges, Bertrand; Brien, James D; Lund, Frances E; Roberts, M Scot

Pulmonary surfactant lipids inhibit infections with the pandemic H1N1 influenza virus in several animal models

肺表面活性物质脂质在多种动物模型中抑制大流行性H1N1流感病毒的感染

Numata, Mari; Mitchell, James R; Tipper, Jennifer L; Brand, Jeffrey D; Trombley, John E; Nagashima, Yoji; Kandasamy, Pitchaimani; Chu, Hong Wei; Harrod, Kevin S; Voelker, Dennis R

Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 in mice

单次鼻内给药AdCOVID可在小鼠体内诱导针对SARS-CoV-2的全身性和黏膜免疫。

King, Rodney G; Silva-Sanchez, Aaron; Peel, Jessica N; Botta, Davide; Meza-Perez, Selene; Allie, Rameeza; Schultz, Michael D; Liu, Mingyong; Bradley, John E; Qiu, Shihong; Yang, Guang; Zhou, Fen; Zumaquero, Esther; Simpler, Thomas S; Mousseau, Betty; Killian, John T; Dean, Brittany; Shang, Qiao; Tipper, Jennifer L; Risley, Christopher; Harrod, Kevin S; Feng, Ray; Lee, Young; Shiberu, Bethlehem; Krishnan, Vyjayanthi; Peguillet, Isabelle; Zhang, Jianfeng; Green, Todd; Randall, Troy D; Georges, Bertrand; Lund, Frances E; Roberts, Scot

Integrative "omic" analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes

对实验性菌血症进行整合“组学”分析,发现了一种代谢特征,该特征可将人类脓毒症与全身炎症反应综合征区分开来。

Langley, Raymond J; Tipper, Jennifer L; Bruse, Shannon; Baron, Rebecca M; Tsalik, Ephraim L; Huntley, James; Rogers, Angela J; Jaramillo, Richard J; O'Donnell, Denise; Mega, William M; Keaton, Mignon; Kensicki, Elizabeth; Gazourian, Lee; Fredenburgh, Laura E; Massaro, Anthony F; Otero, Ronny M; Fowler, Vance G Jr; Rivers, Emanuel P; Woods, Chris W; Kingsmore, Stephen F; Sopori, Mohan L; Perrella, Mark A; Choi, Augustine M K; Harrod, Kevin S

Neurovirulence of H5N1 infection in ferrets is mediated by multifocal replication in distinct permissive neuronal cell regions

H5N1病毒感染雪貂的神经毒性是由病毒在不同易感神经元细胞区域的多灶性复制介导的。

Plourde, Jennifer R; Pyles, John A; Layton, R Colby; Vaughan, Sarah E; Tipper, Jennifer L; Harrod, Kevin S