Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node
联合放疗和αPD-L1可通过刺激肿瘤引流淋巴结中的CD8+PD-1+TCF-1+T细胞来增强肿瘤控制。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-58510-1
Shen, Yang; Connolly, Erin; Aiello, Meili; Zhou, Chengjing; Chappa, Prasanthi; Song, Haorui; Tippitak, Patan; Clark, Tarralyn; Cardenas, Maria; Prokhnevska, Nataliya; Mariniello, Annapaola; De Bruyker, Isabelle; Pagadala, Meghana S; Dhere, Vishal R; Rafiq, Sarwish; Kesarwala, Aparna H; Orthwein, Alexandre; Thomas, Susan N; Zhang, Shirley L; Khan, Mohammad K; Dixon, J Brandon; Lesinski, Gregory B; Lowe, Michael C; Kissick, Haydn; Yu, David S; Paulos, Chrystal M; Schmitt, Nicole C; Buchwald, Zachary S
肿瘤
T细胞
肿瘤免疫
CD8
PD-L1
T细胞
细胞生物学
PD-1
免疫/内分泌
