日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus treatment in a clinical trial.

临床试验中,单次溶瘤病毒治疗后,T 细胞持续活化并表现出对胶质母细胞瘤的细胞毒性。

Meylan Maxime, Tian Ye, Wu Lijian, Ling Alexander L, Kovarsky Daniel, Barlow Graham L, Nguyen Linh D, Pyrdol Jason, Marx Sascha, Westphal Lucas, Michel Julius, Gonzalez Castro L Nicolas, Dumont Sydney, Santos Andres, Tirosh Itay, Suvà Mario L, Chiocca E Antonio, Wucherpfennig Kai W

Special Issue: The Evolving Landscape of Single-Cell Genomics in CNS and PNS Oncology

特刊:中枢神经系统和周围神经系统肿瘤单细胞基因组学的发展现状

Ellenbogen, Yosef; Suva, Mario L; Tirosh, Itay

Pitfalls in analysis and interpretation of single-cell RNA-seq data in cancer

癌症单细胞RNA测序数据分析和解释中的陷阱

Tirosh, Itay

Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer

胶质母细胞瘤皮质类器官重现细胞状态异质性和细胞间转移

Mangena, Vamsi; Chanoch-Myers, Rony; Sartore, Rafaela; Paulsen, Bruna; Gritsch, Simon; Weisman, Hannah; Hara, Toshiro; Breakefield, Xandra O; Breyne, Koen; Regev, Aviv; Chung, Kwanghun; Arlotta, Paola; Tirosh, Itay; Suvà, Mario L

The multilayered transcriptional architecture of glioblastoma ecosystems.

胶质母细胞瘤生态系统的多层转录结构

Nomura Masashi, Spitzer Avishay, Johnson Kevin C, Garofano Luciano, Nehar-Belaid Djamel, Galili Darnell Noam, Greenwald Alissa C, Bussema Lillian, Oh Young Taek, Varn Frederick S, D'Angelo Fulvio, Gritsch Simon, Anderson Kevin J, Migliozzi Simona, Gonzalez Castro L Nicolas, ChowdhFury Tamrin, Robine Nicolas, Reeves Catherine, Park Jong Bae, Lipsa Anuja, Hertel Frank, Golebiewska Anna, Niclou Simone P, Nusrat Labeeba, Kellet Sorcha, Das Sunit, Moon Hyo Eun, Paek Sun Ha, Bielle Franck, Laurenge Alice, Di Stefano Anna Luisa, Mathon Bertrand, Picca Alberto, Sanson Marc, Tanaka Shota, Saito Nobuhito, Ashley David M, Keir Stephen T, Ligon Keith L, Huse Jason T, Yung W K Alfred, Lasorella Anna, Verhaak Roel G W, Iavarone Antonio, Suvà Mario L, Tirosh Itay

A single-cell atlas of Schwannoma across genetic backgrounds and anatomic locations.

跨遗传背景和解剖位置的神经鞘瘤单细胞图谱

Gonzalez Castro L Nicolas, Gavish Avishai, Bussema Lillian, Mount Christopher W, Neftel Cyril, Nomura Masashi, Chiocca E Antonio, Bi Wenya Linda, Arnaout Omar, Barker Fred G 2nd, Brown Justin M, Jordan Justin T, Batchelor Tracy T, Stemmer-Rachamimov Anat, Plotkin Scott R, Tirosh Itay, Suvà Mario L

Oncogenic IDH1(mut) drives robust loss of histone acetylation and increases chromatin heterogeneity

致癌的IDH1(突变)导致组蛋白乙酰化水平显著降低,并增加染色质异质性。

Furth, Noa; Cohen, Niv; Spitzer, Avishay; Salame, Tomer-Meir; Dassa, Bareket; Mehlman, Tevie; Brandis, Alexander; Moussaieff, Arieh; Friedmann-Morvinski, Dinorah; Castro, Maria G; Fortin, Jerome; Suvà, Mario L; Tirosh, Itay; Erez, Ayelet; Ron, Guy; Shema, Efrat

Single-cell transcriptomic analysis of HPV-related multiphenotypic sinonasal carcinoma uncovers MYB-HPV association

对HPV相关多表型鼻窦癌的单细胞转录组分析揭示了MYB-HPV关联

Wizel, Avishai; Spence, Matthew D A; Mints, Michael; Britton, William; Okolo, Ogoegbunam; Yu, Victoria; Cioffi, Isabel; Caruana, Salvatore; Troob, Scott H; Faquin, William C; Lin, Derrick T; Tirosh, Itay; Puram, Sidharth V; Parikh, Anuraag S; Drier, Yotam

Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single-cell RNA sequencing

单细胞RNA测序揭示小肠神经内分泌肿瘤的亚型和增殖模式

Somech, Einav; Halder, Debdatta; Spitzer, Avishay; Barbolin, Chaya; Tyler, Michael; Halperin, Reut; Biton, Moshe; Tirosh, Amit; Tirosh, Itay

Mutant IDH silences GSX2 to reprogram neural progenitor cell fate and promote gliomagenesis

突变型IDH沉默GSX2,从而重编程神经祖细胞命运并促进胶质瘤发生

Xiao, Yi; Shi, Diana D; Guo, Lei; Neumann, Ethan; Levitt, Michael M; Kaphle, Pranita; Shipman, Tracey; Li, Haocheng; Cai, Feng; Ramirez, Denise M O; Zacharias, Lauren G; Chen, Zhenkang; Lin, Mathew; Puliyappadamba, Vinesh T; Chen, Tao; Savani, Milan R; Peña, Salvador; Wansapura, Janaka; Mathews, Thomas P; Mishra, Prashant; Kim, Yoon Jung; Raj, Prithvi; Richardson, Timothy E; Xu, Jian; Mack, Stephen C; Rahme, Gilbert J; Bernstein, Bradley E; DeBerardinis, Ralph J; Tirosh, Itay; Suvà, Mario L; Xu, Lin; Abdullah, Kalil G; McBrayer, Samuel K