Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins.
重新评估在透化血癌细胞上测试维奈托克或其他 BH3 模拟剂的试验,这些药物选择性地靶向促生存 BCL2 蛋白
期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-025-01487-7
Gong Jia-Nan, Djajawi Tirta M, Moujalled Donia M, Pomilio Giovanna, Khong Tiffany, Zhang Li-Ping, Fedele Pasquale L, Low Michael S, Anderson Mary Ann, Riffkin Christopher D, White Christine A, Lan Ping, Lessene Guillaume, Herold Marco J, Strasser Andreas, Spencer Andrew, Grigoriadis George, Wei Andrew H, van Delft Mark F, Roberts Andrew W, Huang David C S