日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD39 polymorphism enables lung thrombosis in sickle cell disease.

CD39 多态性可导致镰状细胞病患者发生肺血栓形成。

Brzoska Tomasz, Kaminski Tomasz W, Katoch Omika, Menchikova Elizaveta V, Alagbe Adekunle E, Tashbook Sarah E, Tofovic Stevan P, Jonassaint Jude C, St Croix Claudette M, Watkins Simon C, Howe Shane, Field Joshua J, Seyerle Amanda A, Pradhan-Sundd Tirthadipa, Laurie Cecilia, Pankratz Nathan D, Smith Nicholas L, Goode Ellen L, Pankow James S, Kooperberg Charles, Kato Gregory J, Zhang Yingze, Novelli Enrico M, Gladwin Mark T, Jackson Edwin K, Nouraie Seyed M, Sundd Prithu

Heme-Oxygenase 1 Mediated Activation of Cyp3A11 Protects Against Non-Steroidal Pain Analgesics Induced Acute Liver Damage in Sickle Cell Disease Mice.

血红素加氧酶 1 介导的 Cyp3A11 激活可保护镰状细胞病小鼠免受非甾体类镇痛药引起的急性肝损伤

Vats Ravi, Ungalara Ramakrishna, Dubey Rikesh K, Sundd Prithu, Pradhan-Sundd Tirthadipa

Small-molecule inhibitor screen to identify mechanisms of sickle hemoglobin clearance by liver endothelium

利用小分子抑制剂筛选来揭示肝脏内皮清除镰状血红蛋白的机制。

Kaminski, Tomasz W; Zhang, Hong; Katoch, Omika; Shi, Qizhen; Kato, Gregory J; Sundd, Prithu; Pradhan-Sundd, Tirthadipa

Impaired hemoglobin clearance by sinusoidal endothelium promotes vaso-occlusion and liver injury in sickle cell disease

镰状细胞病中,肝窦内皮清除血红蛋白功能受损会促进血管阻塞和肝损伤。

Kaminski, Tomasz W; Katoch, Omika; Li, Ziming; Hanway, Corrine B; Dubey, Rikesh K; Alagbe, Adekunle; Brzoska, Tomasz; Zhang, Hong; Sundd, Prithu; Kato, Gregory J; Novelli, Enrico M; Pradhan-Sundd, Tirthadipa

Lung microvascular occlusion by platelet-rich neutrophil-platelet aggregates promotes cigarette smoke-induced severe flu

富含血小板的中性粒细胞-血小板聚集体导致肺微血管闭塞,从而引发香烟烟雾诱发的严重流感

Tomasz W Kaminski, Tomasz Brzoska, Xiuying Li, Ravi Vats, Omika Katoch, Rikesh K Dubey, Kamal Bagale, Simon C Watkins, Bryan J McVerry, Tirthadipa Pradhan-Sundd, Lianghui Zhang, Keven M Robinson, Toru Nyunoya, Prithu Sundd

Hemoglobin scavenger receptor CD163 as a potential biomarker of hemolysis-induced hepatobiliary injury in sickle cell disease

血红蛋白清道夫受体 CD163 是镰状细胞病溶血诱发肝胆损伤的潜在生物标志物

Tomasz W Kaminski, Ayyanar Sivanantham, Anna Mozhenkova, Ashley Smith, Ramakrishna Ungalara, Rikesh K Dubey, Bibhav Shrestha, Corrine Hanway, Omika Katoch, Jesús Tejero, Prithu Sundd, Enrico M Novelli, Gregory J Kato, Tirthadipa Pradhan-Sundd

Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease

长期 L-谷氨酰胺治疗可减少镰状细胞病小鼠模型中的溶血,而不会改善肝血管闭塞和肝纤维化

Omika Katoch, Ramakrishna Ungalara, Tomasz Kaminski, Ziming Li, Rikesh K Dubey, Isabella Burholt, Shweta Gudapati, Tirthadipa Pradhan-Sundd

Liver-to-lung microembolic NETs promote gasdermin D-dependent inflammatory lung injury in sickle cell disease

肝肺微栓塞NETs促进镰状细胞病中gasdermin D依赖性炎症性肺损伤

Vats, Ravi; Kaminski, Tomasz W; Brzoska, Tomasz; Leech, John A; Tutuncuoglu, Egemen; Katoch, Omika; Jonassaint, Jude; Tejero, Jesus; Novelli, Enrico M; Pradhan-Sundd, Tirthadipa; Gladwin, Mark T; Sundd, Prithu

Defenestrated endothelium delays liver-directed gene transfer in hemophilia A mice

内皮细胞窗孔缺失会延缓A型血友病小鼠肝脏定向基因转移。

Kaminski, Tomasz W; Ju, Eun-Mi; Gudapati, Shweta; Vats, Ravi; Arshad, Sanya; Dubey, Rikesh K; Katoch, Omika; Tutuncuoglu, Egemen; Frank, Jonathan; Brzoska, Tomasz; Stolz, Donna B; Watkins, Simon C; Chan, Stephen Y; Ragni, Margaret V; Novelli, Enrico M; Sundd, Prithu; Pradhan-Sundd, Tirthadipa

Molecular mechanisms of hepatic dysfunction in sickle cell disease: lessons from Townes mouse model

镰状细胞病肝功能障碍的分子机制:来自 Townes 小鼠模型的启示

Pradhan-Sundd, Tirthadipa; Kato, Gregory J; Novelli, Enrico M