日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multifaceted approach toward mapping out the anticancer properties of small molecules via in vitro evaluation on melanoma and nonmelanoma skin cancer cells, and in silico target fishing

通过对黑色素瘤和非黑色素瘤皮肤癌细胞进行体外评估以及计算机模拟靶向钓鱼,采用多方面方法确定小分子的抗癌特性

Samuel T Boateng, Tithi Roy, Mercy E Agbo, Md Ashiq Mahmud, Sergette Banang-Mbeumi, Roxane-Cherille N Chamcheu, Rajesh K Yadav, Marion Bramwell, Long K Pham, Danny D Dang, Keith E Jackson, Bolni Marius Nagalo, Ronald A Hill, Tatiana Efimova, Jean Fotie, Jean Christopher Chamcheu

Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation

漆黄素对 mTOR/IL-17A 和自噬的双重靶向作用可缓解银屑病样皮肤炎症

Tithi Roy, Sergette Banang-Mbeumi, Samuel T Boateng, Emmanuelle M Ruiz, Roxane-Cherille N Chamcheu, Lin Kang, Judy A King, Anthony L Walker, Bolni Marius Nagalo, Konstantin G Kousoulas, Stephane Esnault, Shile Huang, Jean Christopher Chamcheu

Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents

取代吡唑衍生物作为潜在抗皮肤癌、抗酪氨酸酶和抗氧化剂的合成、计算机模拟和体外生物学评价

Samuel T Boateng, Tithi Roy, Kara Torrey, Uchechi Owunna, Sergette Banang-Mbeumi, David Basnet, Eleonora Niedda, Alexis D Alexander, Denzel El Hage, Siriki Atchimnaidu, Bolni Marius Nagalo, Dinesh Aryal, Ann Findley, Navindra P Seeram, Tatiana Efimova, Mario Sechi, Ronald A Hill, Hang Ma, Jean Chris

Standardized Pomegranate (Pomella®) and Red Maple (Maplifa®) Extracts and Their Phenolics Protect Type I Collagen by the Inhibition of Matrix Metalloproteinases, Collagenase, and Collagen Cross-Linking

标准化石榴 (Pomella®) 和红枫 (Maplifa®) 提取物及其酚类物质通过抑制基质金属蛋白酶、胶原酶和胶原交联来保护 I 型胶原蛋白

Huifang Li, Tithi Roy, Samuel T Boateng, Hao He, Chang Liu, Weixi Liu, Dongli Li, Panpan Wu, Navindra P Seeram, Jean Christopher Chamcheu, Hang Ma

Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers

合成、逆向对接辅助鉴定和体外生物学表征基于黄酮醇的fisetin类似物作为c-Kit、CDK2和mTOR抑制剂对抗黑色素瘤和非黑色素瘤皮肤癌

Tithi Roy, Samuel T Boateng, Sergette Banang-Mbeumi, Pankaj K Singh, Pratik Basnet, Roxane-Cherille N Chamcheu, Federico Ladu, Isabel Chauvin, Vladimir S Spiegelman, Ronald A Hill, Konstantin G Kousoulas, Bolni Marius Nagalo, Anthony L Walker, Jean Fotie, Siva Murru, Mario Sechi, Jean Christopher Ch

Chronic Metabolic Acidosis Elicits Hypertension via Upregulation of Intrarenal Angiotensin II and Induction of Oxidative Stress

慢性代谢性酸中毒通过上调肾内血管紧张素 II 和诱导氧化应激引起高血压

Dinesh Aryal, Tithi Roy, Jean Christopher Chamcheu, Keith E Jackson

Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

3,7,3',4'-四羟基黄酮非瑟黄素可抑制 PI3K/Akt/mTOR 和 MAPK 通路,改善 2D 和 3D 器官型人类炎症皮肤模型中的银屑病病理

Jean Christopher Chamcheu, Stephane Esnault, Vaqar M Adhami, Andrea L Noll, Sergette Banang-Mbeumi, Tithi Roy, Sitanshu S Singh, Shile Huang, Konstantin G Kousoulas, Hasan Mukhtar