日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-omics whole-genome characterization of the copy number landscape of metastatic pancreatic ductal adenocarcinoma

转移性胰腺导管腺癌拷贝数图谱的多组学全基因组表征

Topham, James T; Karasinska, Joanna M; Metcalfe, Andrew; Ali, Hassan A; Kalloger, Steve E; Kevorkova, Maya; Titmuss, Emma; Negri, Gian Luca; Spencer, Sandra E; Jang, Gun Ho; O'Kane, Grainne M; Moore, Richard A; Mungall, Andrew J; Loree, Jonathan M; Notta, Faiyaz; Wilson, Julie M; Bathe, Oliver F; Tang, Patricia A; Goodwin, Rachel; Morin, Gregg B; Knox, Jennifer J; Gallinger, Steven; Laskin, Janessa; Marra, Marco A; Jones, Steven J M; Renouf, Daniel J; Schaeffer, David F

Clonal Hematopoiesis of Indeterminate Potential and its Association with Treatment Outcomes and Adverse Events in Patients with Solid Tumors

克隆性造血功能不明及其与实体瘤患者治疗结果和不良事件的关系

Krishnan, Tharani; Solar Vasconcelos, Joao Paulo; Titmuss, Emma; Vanner, Robert J; Schaeffer, David F; Karsan, Aly; Lim, Howard; Ho, Cheryl; Gill, Sharlene; Yip, Stephen; Chia, Stephen K; Kennecke, Hagen F; Jonker, Derek J; Chen, Eric X; Renouf, Daniel J; O'Callaghan, Chris J; Loree, Jonathan M

Whole genome and transcriptome integrated analyses guide clinical care of pediatric poor prognosis cancers

全基因组和转录组整合分析指导儿童预后不良癌症的临床治疗

Deyell, Rebecca J; Shen, Yaoqing; Titmuss, Emma; Dixon, Katherine; Williamson, Laura M; Pleasance, Erin; Nelson, Jessica M T; Abbasi, Sanna; Krzywinski, Martin; Armstrong, Linlea; Bonakdar, Melika; Ch'ng, Carolyn; Chuah, Eric; Dunham, Chris; Fok, Alexandra; Jones, Martin; Lee, Anna F; Ma, Yussanne; Moore, Richard A; Mungall, Andrew J; Mungall, Karen L; Rogers, Paul C; Schrader, Kasmintan A; Virani, Alice; Wee, Kathleen; Young, Sean S; Zhao, Yongjun; Jones, Steven J M; Laskin, Janessa; Marra, Marco A; Rassekh, Shahrad R

Plasma arginine as a predictive biomarker for outcomes with immune checkpoint inhibition in metastatic colorectal cancer: a correlative analysis of the CCTG CO.26 trial

血浆精氨酸作为转移性结直肠癌免疫检查点抑制剂疗效的预测性生物标志物:CCTG CO.26试验的相关性分析

Ma, Lucy X; Titmuss, Emma; Loree, Jonathan M; Jonker, Derek J; Kennecke, Hagen F; Berry, Scott; Couture, Felix; Ahmad, Chaudhary E; Goffin, John R; Kavan, Petr; Harb, Mohammed; Colwell, Bruce; Samimi, Setareh; Samson, Benoit; Abbas, Tahir; Aucoin, Nathalie; Aubin, Francine; Koski, Sheryl; Tu, Dongsheng; O'Callaghan, Christopher; Chen, Eric X

Transverse Colon Primary Tumor Location as a Biomarker in Metastatic Colorectal Cancer: A Pooled Analysis of CCTG/AGITG CO.17 and CO.20 Randomized Clinical Trials

横结肠原发肿瘤位置作为转移性结直肠癌的生物标志物:CCTG/AGITG CO.17 和 CO.20 随机临床试验的汇总分析

Solar Vasconcelos, Joao Paulo; Chen, Nan; Titmuss, Emma; Tu, Dongsheng; Brule, Stephanie Y; Goodwin, Rachel; Jonker, Derek J; Price, Timothy; Zalcberg, John R; Moore, Malcolm J; Karapetis, Christos S; Siu, Lillian; Shapiro, Jeremy; Simes, John; Gill, Sharlene; O'Callaghan, Chris J; Loree, Jonathan M

Plasma versus Tissue Tumor Mutational Burden as Biomarkers of Durvalumab plus Tremelimumab Response in Patients with Metastatic Colorectal Cancer in the CO.26 Trial

在CO.26试验中,血浆与组织肿瘤突变负荷作为转移性结直肠癌患者接受度伐利尤单抗联合曲美利尤单抗治疗反应的生物标志物

Loree, Jonathan M; Titmuss, Emma; Topham, James T; Kennecke, Hagen F; Feilotter, Harriet; Virk, Shakeel; Lee, Young S; Banks, Kimberly; Quinn, Katie; Karsan, Aly; Renouf, Daniel J; Jonker, Derek J; Tu, Dongsheng; O'Callaghan, Chris J; Chen, Eric X

Exploration of Germline Correlates and Risk of Immune-Related Adverse Events in Advanced Cancer Patients Treated with Immune Checkpoint Inhibitors

探索接受免疫检查点抑制剂治疗的晚期癌症患者的种系相关性及免疫相关不良事件风险

Titmuss, Emma; Yu, Irene S; Pleasance, Erin D; Williamson, Laura M; Mungall, Karen; Mungall, Andrew J; Renouf, Daniel J; Moore, Richard; Jones, Steven J M; Marra, Marco A; Laskin, Janessa J; Savage, Kerry J

Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial

肝转移和免疫检查点抑制剂治疗难治性转移性结直肠癌患者的疗效:一项随机临床试验的二次分析

Chen, Eric X; Loree, Jonathan M; Titmuss, Emma; Jonker, Derek J; Kennecke, Hagen F; Berry, Scott; Couture, Felix; Ahmad, Chaudharry E; Goffin, John R; Kavan, Petr; Harb, Mohammed; Colwell, Bruce; Samimi, Setareh; Samson, Benoit; Abbas, Tahir; Aucoin, Nathalie; Aubin, Francine; Koski, Sheryl; Wei, Alice C; Tu, Dongsheng; O'Callaghan, Chris J

Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers

趋化因子表达可预测T细胞炎症,并可通过免疫检查点抑制剂治疗提高实体瘤的生存率。

Romero, Joan Miguel; Titmuss, Emma; Wang, Yifan; Vafiadis, James; Pacis, Alain; Jang, Gun Ho; Zhang, Amy; Golesworthy, Bryn; Lenko, Tatiana; Williamson, Laura M; Grünwald, Barbara; O'Kane, Grainne M; Jones, Steven J M; Marra, Marco A; Wilson, Julie M; Gallinger, Steven; Laskin, Janessa; Zogopoulos, George

Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

胃肠道和胸部肿瘤中同源重组缺陷的特征与铂类药物治疗持续时间相关。

Tsang, Erica S; Csizmok, Veronika; Williamson, Laura M; Pleasance, Erin; Topham, James T; Karasinska, Joanna M; Titmuss, Emma; Schrader, Intan; Yip, Stephen; Tessier-Cloutier, Basile; Mungall, Karen; Ng, Tony; Sun, Sophie; Lim, Howard J; Loree, Jonathan M; Laskin, Janessa; Marra, Marco A; Jones, Steven J M; Schaeffer, David F; Renouf, Daniel J