日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Reactivation of developmentally silenced globin genes through forced linear recruitment of remote enhancers

通过强制线性募集远端增强子来重新激活发育过程中沉默的珠蛋白基因

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2024028128
Felder, Anna-Karina; Tjalsma, Sjoerd J D; Verhagen, Han J M P; Majied, Rezin; Verstegen, Marjon J A M; Verheul, Thijs C J; van Haren, Jeffrey; Mohnani, Rebecca; Gremmen, Richard; Krijger, Peter H L; Philipsen, Sjaak; van den Akker, Emile; de Laat, Wouter
发育与干细胞
发表日期：2025
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Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations.

长程增强子控制的基因对调控因子扰动高度敏感

期刊:Cell Genomics
影响因子:9
doi:10.1016/j.xgen.2025.100778
Tjalsma Sjoerd J D, Rinzema Niels J, Verstegen Marjon J A M, Robers Michelle J, Nieto-Aliseda Andrea, Gremmen Richard A, Allahyar Amin, Muraro Mauro J, Krijger Peter H L, de Laat Wouter
其它
发表日期：2025
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Nutritional support in pancreatic cancer patients and its effect on nutritional status: an observational regional HPB network study investigating current practice

胰腺癌患者的营养支持及其对营养状况的影响：一项针对当前实践的区域性肝胆胰网络观察性研究

期刊:Supportive Care in Cancer
影响因子:3
doi:10.1007/s00520-024-08683-0
Wijma, Allard G; Hogenbirk, Rianne N M; Driessens, Heleen; Kluifhooft, Daniëlle A; Jellema-Betten, Ellen S; Tjalsma-de Vries, Marlies; Liem, Mike S L; Nieuwenhuijs, Vincent B; Manusama, Eric M; Hoogwater, Frederik J H; Nijkamp, Maarten W; Beijer, Sandra; Klaase, Joost M
胰腺癌
肿瘤
肿瘤免疫
发表日期：2024
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Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization

细胞因子CTCF在调控牛白血病病毒潜伏期和三维染色质组织中的作用

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkac107
Bellefroid, Maxime; Rodari, Anthony; Galais, Mathilde; Krijger, Peter H L; Tjalsma, Sjoerd J D; Nestola, Lorena; Plant, Estelle; Vos, Erica S M; Cristinelli, Sara; Van Driessche, Benoit; Vanhulle, Caroline; Ait-Ammar, Amina; Burny, Arsène; Ciuffi, Angela; de Laat, Wouter; Van Lint, Carine
信号转导
白血病
微生物学
CTCF
细胞生物学
免疫/内分泌
发表日期：2022
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Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes

构建调控景观表明，增强子可以招募黏连蛋白来创建接触域、接合 CTCF 位点并激活远距离基因

期刊:Nature Structural & Molecular Biology
影响因子:12.5
doi:10.1038/s41594-022-00787-7
Niels J Rinzema, Konstantinos Sofiadis, Sjoerd J D Tjalsma, Marjon J A M Verstegen, Yuva Oz, Christian Valdes-Quezada, Anna-Karina Felder, Teodora Filipovska, Stefan van der Elst, Zaria de Andrade Dos Ramos, Ruiqi Han, Peter H L Krijger, Wouter de Laat
信号转导
IHC
IP
WB
SMC1
发表日期：2022
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H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing

H4K20me1 和 H3K27me3 同时加载到失活的 X 染色体上，但对于诱导基因沉默而言并非必需的

期刊:EMBO Reports
影响因子:6.5
doi:10.15252/embr.202051989
Sjoerd J D Tjalsma, Mayako Hori, Yuko Sato, Aurelie Bousard, Akito Ohi, Ana Cláudia Raposo, Julia Roensch, Agnes Le Saux, Jumpei Nogami, Kazumitsu Maehara, Tomoya Kujirai, Tetsuya Handa, Sandra Bagés-Arnal, Yasuyuki Ohkawa, Hitoshi Kurumizaka, Simão Teixeira da Rocha, Jan J Żylicz, Hiroshi Kimura, E
表观遗传
发表日期：2021
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Streptococcus gallolyticus Increases Expression and Activity of Aryl Hydrocarbon Receptor-Dependent CYP1 Biotransformation Capacity in Colorectal Epithelial Cells

解没食子酸链球菌增强结直肠上皮细胞中芳基烃受体依赖性 CYP1 生物转化能力的表达和活性

期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.6
doi:10.3389/fcimb.2021.740704
Rahwa Taddese, Rian Roelofs, Derk Draper, Xinqun Wu, Shaoguang Wu, Dorine W Swinkels, Harold Tjalsma, Annemarie Boleij
微生物学
细胞生物学
上皮细胞
发表日期：2021
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Antibody responses to flagellin C and Streptococcus gallolyticus pilus proteins in colorectal cancer

结直肠癌中针对鞭毛蛋白C和溶血链球菌菌毛蛋白的抗体反应

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-019-47347-6
Butt, Julia; Fernández de Larrea, Nerea; Tjalsma, Harold; Roelofs, Rian; Kato, Ikuko; Martín, Vicente; Pérez-Gómez, Beatriz; Moreno, Victor; Dierssen-Sotos, Trinidad; Castilla, Jesús; Fernández-Tardón, Guillermo; Amiano, Pilar; Salas, Dolores; Alguacil, Juan; Jiménez-Moleón, José Juan; Huerta, José María; de Sanjosé, Silvia; Del Campo, Rosa; Kogevinas, Manolis; Pollán, Marina; Pawlita, Michael; Waterboer, Tim; Boleij, Annemarie; Aragonés, Nuria
肿瘤
肠癌
肿瘤免疫
发表日期：2019
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The mixed lineage leukemia 4 (MLL4) methyltransferase complex is involved in transforming growth factor beta (TGF-β)-activated gene transcription

混合谱系白血病 4 (MLL4) 甲基转移酶复合物参与转化生长因子 β (TGF-β) 激活的基因转录

期刊:Transcription-Austin
影响因子:3.6
doi:10.1080/21541264.2017.1373890
Roy Baas, Hetty A A M van Teeffelen, Sjoerd J D Tjalsma, H Th Marc Timmers
信号转导
肿瘤
白血病
TGF-β
发表日期：2018
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Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens

低膳食铁摄入量可抑制食源性细菌病原体的肠道炎症反应和肠道感染病理

期刊:European Journal of Immunology
影响因子:4.5
doi:10.1002/eji.201545642
Guus A M Kortman, Michelle L M Mulder, Thijs J W Richters, Nanda K N Shanmugam, Estela Trebicka, Jos Boekhorst, Harro M Timmerman, Rian Roelofs, Erwin T Wiegerinck, Coby M Laarakkers, Dorine W Swinkels, Albert Bolhuis, Bobby J Cherayil, Harold Tjalsma
免疫
微生物学
肠炎
发表日期：2015
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