日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation.

CRAF/MEK1/14-3-3 复合物在自身抑制和开放单体状态下的冷冻电镜结构揭示了 RAF 调控的特征

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63227-2
Jang Dong Man, Boxer Kayla, Ha Byung Hak, Tkacik Emre, Levitz Talya, Rawson Shaun, Metivier Rebecca J, Schmoker Anna, Jeon Hyesung, Eck Michael J
信号转导
发表日期：2025
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Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF kinases

ARAF、BRAF 和 CRAF 激酶的特性及抑制剂敏感性

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110800
Tkacik, Emre; Jang, Dong Man; Boxer, Kayla; Ha, Byung Hak; Eck, Michael J
信号转导
ARAF
BRAF
发表日期：2025
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RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor

MEK抑制剂的RAF亚型选择性及共价ARAF-MEK抑制剂的合理设计

期刊:
影响因子:
doi:10.64898/2025.12.15.693503
Chakraborty, Sayan; Jiang, Jie; Camallonga, Javier Vinals; Gazgalis, Dimitris; Gero, Thomas W; Tavares, Maurício T; Dittemore, Georgia; Tkacik, Emre; Jang, Dong Man; Ha, Byung Hak; Gottlieb, Felix H; Levitz, Talya; Metivier, Rebecca J; Schmoker, Anna M; Scott, David A; Jeon, Hyesung; Jänne, Pasi A; Eck, Michael J
ARAF
发表日期：2025
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Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib

II 型 RAF 抑制剂托沃拉非尼和萘普拉非尼的结构和 RAF 家族激酶亚型选择性

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2023.104634
Tkacik, Emre; Li, Kunhua; Gonzalez-Del Pino, Gonzalo; Ha, Byung Hak; Vinals, Javier; Park, Eunyoung; Beyett, Tyler S; Eck, Michael J
信号转导
发表日期：2023
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