Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models
选择性铜绿假单胞菌 LasB 弹性蛋白酶抑制剂的化学优化及其对细胞和动物感染模型中 LasB 介导的 IL-1β 激活的影响
期刊:ACS Infectious Diseases
影响因子:4
doi:10.1021/acsinfecdis.2c00418
Martin J Everett, David T Davies, Simon Leiris, Nicolas Sprynski, Agustina Llanos, Jérôme M Castandet, Clarisse Lozano, Christopher N LaRock, Doris L LaRock, Giuseppina Corsica, Jean-Denis Docquier, Thomas D Pallin, Andrew Cridland, Toby Blench, Magdalena Zalacain, Marc Lemonnier
