日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells.

对靶向肿瘤细胞的新型胸苷酸合成酶抑制剂 N-[4-[2-丙炔-1-基[(6S)-4,6,7,8-四氢-2-(羟甲基)-4-氧代-3H-环戊并[g]喹唑啉-6-基]氨基]苯甲酰基]-l-γ-谷氨酰-D-谷氨酸 (BGC 945) 进行开发和结合模式评估

Tochowicz Anna, Dalziel Sean, Eidam Oliv, O'Connell Joseph D 3rd, Griner Sarah, Finer-Moore Janet S, Stroud Robert M

The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions

膜型1基质金属蛋白酶血红素结合域的二聚体界面:晶体结构和生物学功能

Tochowicz, Anna; Goettig, Peter; Evans, Richard; Visse, Robert; Shitomi, Yasuyuki; Palmisano, Ralf; Ito, Noriko; Richter, Klaus; Maskos, Klaus; Franke, Daniel; Svergun, Dmitri; Nagase, Hideaki; Bode, Wolfram; Itoh, Yoshifumi