日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes independent of their acetylation activity

ATAC 和 SAGA 组蛋白乙酰转移酶模块促进转录因子与核小体的结合,而与它们的乙酰化活性无关。

Chesnutt, Kristin V; Yayli, Gizem; Toelzer, Christine; Damilot, Mylène; Cox, Khan; Gautam, Gunjan; Berger, Imre; Tora, László; Poirier, Michael G

Crystal structure of ferric recombinant horseradish peroxidase

重组辣根过氧化物酶铁晶体结构

Nesa, Mst Luthfun; Mandal, Suman K; Toelzer, Christine; Humer, Diana; Moody, Peter C E; Berger, Imre; Spadiut, Oliver; Raven, Emma L

Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders

设计 ADDobody 蛋白支架以生成高亲和力的 ADDomer 超级结合剂

Dora Buzas, Huan Sun, Christine Toelzer, Sathish K N Yadav, Ufuk Borucu, Gunjan Gautam, Kapil Gupta, Joshua C Bufton, Julien Capin, Richard B Sessions, Frederic Garzoni, Imre Berger, Christiane Schaffitzel

Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy

冷冻电镜揭示了亚油酸与SARS-CoV-2刺突糖蛋白的结合,提示了一种抗病毒治疗策略。

Toelzer, Christine; Gupta, Kapil; Berger, Imre; Schaffitzel, Christiane

Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation

无义介导的 mRNA 衰变因子 UPF3B 和 UPF3A 与 UPF2 复合的结构揭示了竞争性结合和导致神经发育障碍的突变的分子基础

Joshua C Bufton, Kyle T Powers, Jenn-Yeu A Szeto, Christine Toelzer, Imre Berger, Christiane Schaffitzel

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

利用单个杆状病毒实现高效的 CRISPR 介导的大片段 DNA 对接和多重启动编辑

Francesco Aulicino ,Martin Pelosse ,Christine Toelzer ,Julien Capin ,Erwin Ilegems ,Parisa Meysami ,Ruth Rollarson ,Per-Olof Berggren ,Mark Simon Dillingham ,Christiane Schaffitzel ,Moin A Saleem ,Gavin I Welsh ,Imre Berger

Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

SARS-CoV-2 宿主内多样性细胞类型特异性进化的结构性见解

Kapil Gupta # ,Christine Toelzer # ,Maia Kavanagh Williamson # ,Deborah K Shoemark # ,A Sofia F Oliveira ,David A Matthews ,Abdulaziz Almuqrin ,Oskar Staufer ,Sathish K N Yadav ,Ufuk Borucu ,Frederic Garzoni ,Daniel Fitzgerald ,Joachim Spatz ,Adrian J Mulholland ,Andrew D Davidson ,Christiane Schaffitzel ,Imre Berger

The free fatty acid-binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron

游离脂肪酸结合口袋是 SARS-CoV 至 Omicron 等致病性 β 冠状病毒刺突蛋白中保守的标志

Christine Toelzer, Kapil Gupta, Sathish K N Yadav, Lorna Hodgson, Maia Kavanagh Williamson, Dora Buzas, Ufuk Borucu, Kyle Powers, Richard Stenner, Kate Vasileiou, Frederic Garzoni, Daniel Fitzgerald, Christine Payré, Gunjan Gautam, Gérard Lambeau, Andrew D Davidson, Paul Verkade, Martin Frank, Imre

Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein*

分子模拟表明,维生素、类视黄醇和类固醇可能是SARS-CoV-2刺突蛋白游离脂肪酸口袋的配体*

Shoemark, Deborah K; Colenso, Charlotte K; Toelzer, Christine; Gupta, Kapil; Sessions, Richard B; Davidson, Andrew D; Berger, Imre; Schaffitzel, Christiane; Spencer, James; Mulholland, Adrian J

Frontispiz: Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein

Frontispiz:分子模拟表明,维生素、类视黄醇和类固醇可能是SARS-CoV-2刺突蛋白游离脂肪酸口袋的配体。

Shoemark, Deborah K; Colenso, Charlotte K; Toelzer, Christine; Gupta, Kapil; Sessions, Richard B; Davidson, Andrew D; Berger, Imre; Schaffitzel, Christiane; Spencer, James; Mulholland, Adrian J