日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Higher phosphorylated tau levels predict cognitive decline and amyloid-related imaging abnormalities during lecanemab treatment: clinical practice data

较高的磷酸化tau蛋白水平可预测lecanemab治疗期间的认知功能下降和淀粉样蛋白相关影像学异常：临床实践数据

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-025-01912-6
Noguchi-Shinohara, Moeko; Yoshinobu, Takahiro; Ozaki, Taro; Muramatsu, Daiki; Shima, Ayano; Sakashita, Yasuhiro; Tada, Yasutake; Yamaguchi, Hiroki; Komatsu, Junji; Ikeda, Tokuhei; Ono, Kenjiro
信号转导
磷酸化
神经科学
发表日期：2025
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ALZ-801 prevents amyloid β-protein assembly and reduces cytotoxicity: A preclinical experimental study

ALZ-801 可抑制β-淀粉样蛋白组装并降低细胞毒性：一项临床前实验研究

期刊:FASEB Journal
影响因子:4.2
doi:10.1096/fj.202402622R
Muramatsu, Daiki; Watanabe-Nakayama, Takahiro; Tsuji, Mayumi; Umeda, Kenichi; Hikishima, Sadao; Nakano, Hiroto; Sakashita, Yasuhiro; Ikeda, Tokuhei; Konno, Hiroki; Kodera, Noriyuki; Ando, Toshio; Noguchi-Shinohara, Moeko; Ono, Kenjiro
细胞生物学
毒理研究
发表日期：2025
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Inhibitory Effects of 3-(4-Hydroxy-3-methoxyphenyl) Propionic Acid on Amyloid β-Peptide Aggregation In Vitro

3-(4-羟基-3-甲氧基苯基)丙酸对体外淀粉样β肽聚集的抑制作用

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13071649
Mori, Makoto; Nakano, Hiroto; Hikishima, Sadao; Minamikawa, Jota; Muramatsu, Daiki; Sakashita, Yasuhiro; Ikeda, Tokuhei; Noguchi-Shinohara, Moeko; Ono, Kenjiro
发表日期：2025
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Possible Mechanisms of Amyloid β‐Protein Protofibrils for Acceleration of Aggregation

淀粉样β蛋白原纤维加速聚集的可能机制

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adr8046
Ma, Zongpeng; Solís-Fernández, Pablo; Hirata, Kaito; Lin, Yung-Chang; Shinokita, Keisuke; Maruyama, Mina; Honda, Kota; Kato, Tatsuki; Uchida, Aika; Ogura, Hiroto; Otsuka, Tomohiro; Hara, Masahiro; Matsuda, Kazunari; Suenaga, Kazu; Okada, Susumu; Kato, Toshiaki; Takahashi, Yasufumi; Ago, Hiroki; Nakano, Hiroto; Nakayama, Takahiro; Hikishima, Sadao; Mori, Makoto; Minamikawa, Jota; Muramatsu, Daiki; Sakashita, Yasuhiro; Ikeda, Tokuhei; Shinohara, Moeko; Ono, Kenjiro
发表日期：2024
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Lutein from Chicken Eggs Prevents Amyloid β-Peptide Aggregation In Vitro and Amyloid β-Induced Inflammation in Human Macrophages (THP-1)

鸡蛋中的叶黄素可预防体外淀粉样β肽聚集和淀粉样β诱导的人类巨噬细胞（THP-1）炎症

期刊:ACS Omega
影响因子:3.7
doi:10.1021/acsomega.4c03353
Misuzu Matsui, Tomofusa Murata, Yuki Kurobe-Takashima, Tokuhei Ikeda, Moeko Noguchi-Shinohara, Kenjiro Ono, Hiroyuki Shidara, Kurataka Otsuka, Daisuke Kuriki, Michio Suzuki, Shoko Kobayashi
细胞生物学
巨噬细胞
Human
发表日期：2024
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Aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy treated with qing fei tang: two case reports

清肺汤治疗进行性核上性麻痹并发吸入性肺炎和支气管肺炎：两例病例报告

期刊:Journal of Medical Case Reports
影响因子:0.8
doi:10.1186/s13256-015-0538-3
Nozaki, Ichiro; Kato-Motozaki, Yuko; Ikeda, Tokuhei; Takahashi, Kazuya; Tagami, Atsuro; Ishida, Chiho; Komai, Kiyonobu
肺炎
发表日期：2015
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Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site-specific binding

酚类化合物通过位点特异性结合，阻止β-淀粉样蛋白寡聚化和突触功能障碍。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M111.325456
Ono, Kenjiro; Li, Lei; Takamura, Yusaku; Yoshiike, Yuji; Zhu, Lijun; Han, Fang; Mao, Xian; Ikeda, Tokuhei; Takasaki, Jun-ichi; Nishijo, Hisao; Takashima, Akihiko; Teplow, David B; Zagorski, Michael G; Yamada, Masahito
神经科学
发表日期：2012
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