日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.

NPP-669 是西多福韦的前药，在易感叙利亚仓鼠模型中对人类腺病毒感染具有很高的疗效

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00489-24
Tollefson Ann E, Cline-Smith Anna B, Spencer Jacqueline F, Reyna Dawn M, Lipka Elke, Toth Karoly
Hamster
Human
发表日期：2024
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Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters

口服 USC-093 是一种新型的酪氨酰胺 (S)-HPMPA 前药 USC-087 的高丝氨酸酰胺类似物，在保持对叙利亚仓鼠人类腺病毒感染的抗病毒功效的同时，降低了肾毒性。

期刊:Antiviral Research
影响因子:4
doi:10.1016/j.antiviral.2024.105799
Tollefson, Ann E; Riemann, Samantha B; Ying, Baoling; Spencer, Jacqueline F; Overhulse, Justin M; Kashemirov, Boris A; Wold, William S M; McKenna, Charles E; Toth, Karoly
炎症/感染
毒理研究
微生物学
发表日期：2024
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Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 M(pro) inhibitors with improved metabolic stability

微型化的点击化学和直接筛选技术促进了具有更高代谢稳定性的三唑哌嗪类SARS-CoV-2 M(pro)抑制剂的发现。

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d4md00555d
Gao, Shenghua; Song, Letian; Ye, Bing; Yang, Mianling; Li, Junyi; Gu, Manyu; Tollefson, Ann E; Toth, Karoly; Zhan, Peng; Liu, Xinyong
代谢
SARS-CoV-2
发表日期：2024
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Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model.

在允许的体内模型中对腺病毒治疗方案的效果进行纵向监测

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v16081200
Tollefson Ann E, Cline-Smith Anna, Spencer Jacqueline F, Ying Baoling, Reyna Dawn M, Lipka Elke, James Scott H, Toth Karoly
Viral
发表日期：2024
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Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model

合成 USC-093 并与其前体对映体 USC-093D 在体外和叙利亚仓鼠模型中抗腺病毒活性进行比较

期刊:
影响因子:
doi:10.1101/2024.11.01.621456
Yang, Jiayi; Riemann, Samantha B; Lyu, Jinglei; Feng, Sudi; Bi, Yang; Lentini, Nicholas A; Kang, Inah; Kashemirov, Boris A; Hartline, Caroll B; James, Scott H; Tollefson, Ann E; Cline-Smith, Anna; Toth, Karoly; McKenna, Charles E
微生物学
3D/类器官
发表日期：2024
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Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening

通过基于点击化学的快速筛选鉴定新型1,2,3-三唑靛红衍生物作为有效的SARS-CoV-2 3CLpro抑制剂

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d3md00306j
Jiang, Xiangyi; Li, Jing; Viayna, Antonio; Luque, F Javier; Woodson, Molly; Jing, Lanlan; Gao, Shenghua; Zhao, Fabao; Xie, Minghui; Toth, Karoly; Tavis, John; Tollefson, Ann E; Liu, Xinyong; Zhan, Peng
SARS-CoV-2
发表日期：2023
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Biographical Feature: William S. M. Wold, Ph.D., 1944-2021

人物特写：威廉·S·M·沃尔德博士，1944-2021

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/JVI.01184-21
Toth, Karoly; Tollefson, Ann E; Chinnadurai, G; Bellone, Clifford J; Grandgenett, Duane P; Morrison, Lynda A; Tavis, John E
发表日期：2021
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Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses

菲洛西洛韦是一种强效的体外和体内人类腺病毒抑制剂

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01299-20
Toth, Karoly; Hussein, Islam T M; Tollefson, Ann E; Ying, Baoling; Spencer, Jacqueline F; Eagar, Jessica; James, Scott H; Prichard, Mark N; Wold, William S M; Bowlin, Terry L
微生物学
Human
发表日期：2020
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USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses

USC-087 可保护叙利亚仓鼠免受人源丙型腺病毒的致命攻击

期刊:Antiviral Research
影响因子:4
doi:10.1016/j.antiviral.2018.03.001
Toth, Karoly; Spencer, Jacqueline F; Ying, Baoling; Tollefson, Ann E; Hartline, Caroll B; Richard, Eric T; Fan, Jiajun; Lyu, Jinglei; Kashemirov, Boris A; Harteg, Cheryl; Reyna, Dawn; Lipka, Elke; Prichard, Mark N; McKenna, Charles E; Wold, William S M
微生物学
发表日期：2018
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Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters.

由 AAV9 载体表达的抗腺病毒人工微RNA可抑制免疫抑制的叙利亚仓鼠体内的人类腺病毒感染

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2017.07.002
Schaar Katrin, Geisler Anja, Kraus Milena, Pinkert Sandra, Pryshliak Markian, Spencer Jacqueline F, Tollefson Ann E, Ying Baoling, Kurreck Jens, Wold William S, Klopfleisch Robert, Toth Karoly, Fechner Henry
免疫/内分泌
Human
Viral
发表日期：2017
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