日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficient (68)Ga Labeling of a B7-H3-Targeting Affibody Molecule via Acyclic Tris(hydroxypyridinone) Chelator: Effects on Biodistribution in a Preclinical Model

利用非环状三(羟基吡啶酮)螯合剂对靶向B7-H3的亲和体分子进行高效的(68)Ga标记：对临床前模型中生物分布的影响

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27041713
Tolmachev, Vladimir; Herlina, Amelinda Janice; Papalanis, Eleftherios; A Bezverkhniaia, Ekaterina; Ryer, Eva; Orlova, Anna; Y Frejd, Fredrik; Oroujeni, Maryam
发表日期：2026
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Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging

探索两种代谢稳定的、靶向GRPR的Ga-68标记肽在PET成像中的诊疗潜力

期刊:EJNMMI Radiopharmacy and Chemistry
影响因子:3.3
doi:10.1186/s41181-026-00431-5
Obeid, Karim; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir; Orlova, Anna; Kanellopoulos, Panagiotis
代谢
发表日期：2026
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The Impact of the Injected Mass of the Gastrin-Releasing Peptide Receptor Antagonist on Uptake in Breast Cancer: Lessons from a Phase I Trial of [(99m)Tc]Tc-DB8

注射的胃泌素释放肽受体拮抗剂质量对乳腺癌摄取的影响：[(99m)Tc]Tc-DB8 I期试验的经验教训

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17081000
Bragina, Olga; Chernov, Vladimir; Larkina, Mariia; Varvashenya, Ruslan; Zelchan, Roman; Medvedeva, Anna; Ivanova, Anastasiya; Tashireva, Liubov; Maina, Theodosia; Nock, Berthold A; Kanellopoulos, Panagiotis; Sörensen, Jens; Orlova, Anna; Tolmachev, Vladimir
信号转导
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Phase I Clinical Study with the GRPR-Antagonist [(99m)Tc]Tc-DB8 for SPECT Imaging of Prostate Cancer: Does the Injected Peptide Mass Make a Difference?

使用 GRPR 拮抗剂 [(99m)Tc]Tc-DB8 进行 SPECT 成像检测前列腺癌的 I 期临床研究：注射的肽质量有影响吗？

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17101323
Orlova, Anna; Rybina, Anastasia; Medvedeva, Anna; Zelchan, Roman; Bragina, Olga; Tashireva, Liubov; Larkina, Maria; Varvashenya, Ruslan; Lushnikova, Nadejda; Kanellopoulos, Panagiotis; Maina, Theodosia; Nock, Berthold A; Tolmachev, Vladimir; Chernov, Vladimir
肿瘤
前列腺癌
肿瘤免疫
发表日期：2025
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Targeting of Epithelial Cell Adhesion Molecule-Expressing Malignant Tumors Using an Albumin-Binding Domain-Fused Designed Ankyrin Repeat Protein: Effect of the Molecular Architecture

利用白蛋白结合域融合设计的锚蛋白重复序列蛋白靶向表达上皮细胞黏附分子的恶性肿瘤：分子结构的影响

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26115236
Tolmachev, Vladimir; Vorobyeva, Anzhelika; Rosly, Alia Hani Binti; Garousi, Javad; Liu, Yongsheng; Gräslund, Torbjörn; Papalanis, Eleftherios; Schulga, Alexey; Konovalova, Elena; Orlova, Anna; Deyev, Sergey M; Oroujeni, Maryam
肿瘤
肿瘤免疫
上皮细胞
Adhesion/ECM
细胞生物学
发表日期：2025
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Comparative Preclinical Evaluation of the Tumor-Targeting Properties of Radioiodine and Technetium-Labeled Designed Ankyrin Repeat Proteins for Imaging of Epidermal Growth Factor Receptor Expression in Malignant Tumors

放射性碘和锝标记的定制锚蛋白重复序列蛋白在恶性肿瘤表皮生长因子受体表达成像中的肿瘤靶向特性比较临床前评价

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262110609
Larkina, Mariia; Yanovich, Gleb; Hasnowo, Lutfi Aditya; Varvashenya, Ruslan; Yuldasheva, Feruza; Tretyakova, Maria; Plotnikov, Evgenii; Zelchan, Roman; Schulga, Alexey; Konovalova, Elena; Ziganshin, Rustam; Belousov, Mikhail V; Tolmachev, Vladimir; Deyev, Sergey M
信号转导
肿瘤
肿瘤免疫
发表日期：2025
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IMG-103. Molecular Characterization of Meningiomas with Low SSTR-PET/CT Uptake: Insights from a Case Series

IMG-103. 低SSTR-PET/CT摄取脑膜瘤的分子特征：病例系列研究的启示

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-27886-0
Vorobyeva, Anzhelika; Westerlund, Kristina; Mitran, Bogdan; Altai, Mohamed; Rinne, Sara; Sörensen, Jens; Orlova, Anna; Tolmachev, Vladimir; Karlström, Amelie Eriksson; Biczok, Annamaria; Greve, Tobias; Harter, Patrick; Albert, Nathalie
神经科学
发表日期：2025
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Reduction of Negative Charge in Mercaptoacetyl-Based Chelators Influences the Biodistribution of Prostate-Specific Membrane Antigen-Targeting Pseudopeptides Labeled with Technetium-99m

巯基乙酰基螯合剂中负电荷的减少会影响锝-99m标记的前列腺特异性膜抗原靶向假肽的生物分布

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00428
Bezverkhniaia, Ekaterina; Kanellopoulos, Panagiotis; Rosenström, Ulrika; Tolmachev, Vladimir; Orlova, Anna
发表日期：2025
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Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [(99m)Tc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study

利用新型肽基探针[(99m)Tc]Tc-BQ0413（对前列腺癌特异性膜抗原 (PSMA) 具有皮摩尔级亲和力）进行单光子发射计算机断层扫描成像检测前列腺癌患者PSMA表达：一项I/II期临床研究

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00637
Medvedeva, Anna; Chernov, Vladimir; Larkina, Maria; Rybina, Anastasiya; Zelchan, Roman; Bragina, Olga; Varvashenya, Ruslan; Zebzeeva, Olga; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir; Orlova, Anna
肿瘤
前列腺癌
肿瘤免疫
发表日期：2025
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Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules

放射性金属螯合物对使用放射性标记的亲和体分子进行体内免疫检查点蛋白可视化的影响

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00539
Tolmachev, Vladimir; Papalanis, Eleftherios; Bezverkhniaia, Ekaterina A; Rosly, Alia Hani; Vorobyeva, Anzhelika; Orlova, Anna; Carlqvist, Matilda; Frejd, Fredrik Y; Oroujeni, Maryam
Checkpoint
免疫/内分泌
发表日期：2025
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