Tomchuck相关文献与解析，生知库 | 链接生命科学的每一步

Melissa Bonner ，David Askew ，Vrishabhadev Sathish Kumar ，Suzanne L Tomchuck ，Saada Eid ，Muta Abiff ，Jay T Myers ，Phuong Nguyen ，Justin W A Garyu ，Tyler E Miller ，Alex Yee-Chen Huang

细胞生物学

肿瘤

T细胞

Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages

CDK5调节亚基1（p35）的破坏限制了免疫抑制性M2巨噬细胞的增殖，同时维持了功能性M1巨噬细胞的增殖。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1584791

Zampieri, Juliana R; Choi, Sung Hee; Myers, Jay T; Tomchuck, Suzanne L; Eid, Saada; Askew, David; Huang, Alex Y

Piezo1 restrains proinflammatory response but is essential in T-cell-mediated immunopathology.

Piezo1抑制促炎反应，但在T细胞介导的免疫病理学中起着至关重要的作用

期刊:Journal of Leukocyte Biology

影响因子:3.1

doi:10.1093/jleuko/qiae242

Choi Sung Hee, Santin Alicia, Myers Jay T, Kim Byung-Gyu, Eid Saada, Tomchuck Suzanne L, Kingsley Daniel T, Huang Alex Y

Oral transforming growth factor-beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity

口服转化生长因子-β受体1抑制剂vactosertib通过靶向抑制肿瘤增殖和增强抗肿瘤免疫力来促进骨肉瘤消退。

期刊:Cancer Communications

影响因子:24.9

doi:10.1002/cac2.12589

Choi, Sung Hee; Myers, Jay Thomas; Tomchuck, Suzanne Louise; Bonner, Melissa; Eid, Saada; Kingsley, Daniel Tyler; VanHeyst, Kristen Ashley; Kim, Seong-Jin; Kim, Byung-Gyu; Huang, Alex Yee-Chen

Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer

化疗诱导的中性粒细胞胞外陷阱可抑制小鼠结直肠癌模型中的肿瘤生长

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI175031

Li, Yamu; Wu, Sulin; Zhao, Yiqing; Dinh, Trang; Jiang, Dongxu; Selfridge, J Eva; Myers, George; Wang, Yuxiang; Zhao, Xuan; Tomchuck, Suzanne; Dubyak, George; Lee, Richard T; Estfan, Bassam; Shapiro, Marc; Kamath, Suneel; Mohamed, Amr; Huang, Stanley Ching-Cheng; Huang, Alex Y; Conlon, Ronald; Krishnamurthi, Smitha; Eads, Jennifer; Willis, Joseph E; Khorana, Alok A; Bajor, David; Wang, Zhenghe

Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation

功能性肿瘤细胞内在的STING（而非宿主STING）驱动冷冻消融后的局部和全身抗肿瘤免疫反应及治疗效果。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2022-006608

Mohammad Alshebremi # ，Suzanne L Tomchuck # ，Jay T Myers ，Daniel T Kingsley ，Saada Eid ，Muta Abiff ，Melissa Bonner ，Shahrazad T Saab ，Sung Hee Choi ，Alex Yee-Chen Huang

Oral TGF-βR1 inhibitor Vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity

口服TGF-βR1抑制剂Vactosertib通过靶向抑制肿瘤增殖和增强抗肿瘤免疫力来促进骨肉瘤消退。

期刊:

影响因子:

doi:10.21203/rs.3.rs-2709282/v1

Choi, Sung Hee; Myers, Jay; Tomchuck, Suzanne; Bonner, Melissa; Eid, Saada; Kingsley, Daniel; VanHeyst, Kristen; Kim, Seong-Jin; Kim, Byung-Gyu; Huang, Alex Y

Piezo1 facilitates optimal T cell activation during tumor challenge

Piezo1 促进肿瘤攻击期间 T 细胞的最佳活化

期刊:Oncoimmunology

影响因子:

doi:10.1080/2162402X.2023.2281179

Muta Abiff, Mohammad Alshebremi, Melissa Bonner, Jay T Myers, Byung-Gyu Kim, Suzanne L Tomchuck, Alicia Santin, Daniel Kingsley, Sung Hee Choi, Alex Y Huang

Treatment response and outcome of children with T-cell acute lymphoblastic leukemia expressing the gamma-delta T-cell receptor

表达γ-δT细胞受体的T细胞急性淋巴细胞白血病儿童的治疗反应和结果

期刊:Oncoimmunology

影响因子:

doi:10.1080/2162402X.2019.1599637

Ching-Hon Pui, Deqing Pei, Cheng Cheng, Suzanne L Tomchuck, Scarlett N Evans, Hiroto Inaba, Sima Jeha, Susana C Raimondi, John K Choi, Paul G Thomas, Mari Hashitate Dallas

Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis

通过单细胞分析快速克隆、表达和鉴定配对的 αβ 和 γδ T 细胞受体链

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:

doi:10.1038/mtm.2015.54

Xi-Zhi J Guo, Pradyot Dash, Matthew Calverley, Suzanne Tomchuck, Mari H Dallas, Paul G Thomas

Piezo1 deletion enhances cross-priming of CD8+ T cells by tumor-infiltrating CD11b+ dendritic cells

Piezo1缺失增强了肿瘤浸润CD11b+树突状细胞对CD8+ T细胞的交叉启动作用

Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages

CDK5调节亚基1（p35）的破坏限制了免疫抑制性M2巨噬细胞的增殖，同时维持了功能性M1巨噬细胞的增殖。

Piezo1 restrains proinflammatory response but is essential in T-cell-mediated immunopathology.

Piezo1抑制促炎反应，但在T细胞介导的免疫病理学中起着至关重要的作用

Oral transforming growth factor-beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity

口服转化生长因子-β受体1抑制剂vactosertib通过靶向抑制肿瘤增殖和增强抗肿瘤免疫力来促进骨肉瘤消退。

Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer

化疗诱导的中性粒细胞胞外陷阱可抑制小鼠结直肠癌模型中的肿瘤生长

Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation

功能性肿瘤细胞内在的STING（而非宿主STING）驱动冷冻消融后的局部和全身抗肿瘤免疫反应及治疗效果。

Oral TGF-βR1 inhibitor Vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti-tumor immunity

口服TGF-βR1抑制剂Vactosertib通过靶向抑制肿瘤增殖和增强抗肿瘤免疫力来促进骨肉瘤消退。

Piezo1 facilitates optimal T cell activation during tumor challenge

Piezo1 促进肿瘤攻击期间 T 细胞的最佳活化

Treatment response and outcome of children with T-cell acute lymphoblastic leukemia expressing the gamma-delta T-cell receptor

表达γ-δT细胞受体的T细胞急性淋巴细胞白血病儿童的治疗反应和结果

Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis

通过单细胞分析快速克隆、表达和鉴定配对的 αβ 和 γδ T 细胞受体链