日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

N-glycosylation of PD-L1 modulates the efficacy of immune checkpoint blockades targeting PD-L1 and PD-1

PD-L1的N-糖基化调节靶向PD-L1和PD-1的免疫检查点阻断疗法的疗效。

Bar Kaufman ,Muhammad Abu-Ahmad ,Olga Radinsky ,Eman Gharra ,Tal Manko ,Baisali Bhattacharya ,Daniela Gologan ,Nofar Erlichman ,Tsipi Meshel ,Yoav Nuta ,Tomer Cooks ,Moshe Elkabets ,Adit Ben-Baruch ,Angel Porgador

APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based radiotherapy

APR-246 作为针对接受基于阿尔法粒子的放射治疗的突变型 p53 癌症的放射增敏策略

Or Michaeli, Ishai Luz, Maayan Vatarescu, Tal Manko, Noam Weizman, Yevgeniya Korotinsky, Alexandra Tsitrina, Alex Braiman, Lior Arazi, Tomer Cooks

Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development

嗜酸杆菌(Acidovorax temperans)可干扰中性粒细胞成熟并极化Th17细胞,从而促进肺腺癌的发生发展。

Joshua K Stone ,Natalia von Muhlinen ,Chenran Zhang ,Ana I Robles ,Amy L Flis ,Eleazar Vega-Valle ,Akihiko Miyanaga ,Masaru Matsumoto ,K Leigh Greathouse ,Tomer Cooks ,Giorgio Trinchieri ,Curtis C Harris

Extracellular vesicles of the Gram-positive gut symbiont Bifidobacterium longum induce immune-modulatory, anti-inflammatory effects

革兰氏阳性肠道共生菌长双歧杆菌的细胞外囊泡可诱导免疫调节和抗炎作用

Noa Mandelbaum, Lihan Zhang, Shaqed Carasso, Tamar Ziv, Sapir Lifshiz-Simon, Irina Davidovich, Ishai Luz, Elliot Berinstein, Tal Gefen, Tomer Cooks, Yeshayahu Talmon, Emily P Balskus, Naama Geva-Zatorsky

MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays

MPAPASS软件能够进行拼接式多重、多维EV库分析,并为基于微珠的检测报告提供标准框架。

Joshua A Welsh ,Bryce Killingsworth ,Julia Kepley ,Tim Traynor ,Sean Cook ,Jason Savage ,Jenn Marte ,Min-Jung Lee ,Hoyoung M Maeng ,Michelle L Pleet ,Setty Magana ,André Gorgens ,Cecile L Maire ,Katrin Lamszus ,Franz L Ricklefs ,Maria J Merino ,W Marston Linehan ,Tim Greten ,Tomer Cooks ,Curtis C Harris ,Andrea Apolo ,Asim Abdel-Mageed ,Alexander R Ivanov ,Jane B Trepel ,Matthew Roth ,Mercedes Tkach ,Aleksandar Milosavljevic ,Clotilde Théry ,Amy LeBlanc ,Jay A Berzofsky ,Eytan Ruppin ,Kenneth Aldape ,Kevin Camphausen ,James L Gulley ,Ionita Ghiran ,Steve Jacobson ,Jennifer C Jones

Diffusing alpha-emitters radiation therapy in combination with temozolomide or bevacizumab in human glioblastoma multiforme xenografts

弥散性α发射体放射治疗联合替莫唑胺或贝伐单抗治疗人类多形性胶质母细胞瘤异种移植

Yossi Nishri, Maayan Vatarescu, Ishai Luz, Lior Epstein, Mirta Dumančić, Sara Del Mare, Amit Shai, Michael Schmidt, Lisa Deutsch, Robert B Den, Itzhak Kelson, Yona Keisari, Lior Arazi, Tomer Cooks, Vered Domankevich

Proteomic analysis of necroptotic extracellular vesicles

坏死性凋亡细胞外囊泡的蛋白质组学分析

Inbar Shlomovitz #, Ziv Erlich #, Gali Arad, Liat Edry-Botzer, Sefi Zargarian, Hadar Cohen, Tal Manko, Yifat Ofir-Birin, Tomer Cooks, Neta Regev-Rudzki, Motti Gerlic

Cancer Cells Shuttle Extracellular Vesicles Containing Oncogenic Mutant p53 Proteins to the Tumor Microenvironment

癌细胞将含有致癌突变 p53 蛋白的细胞外囊泡运送到肿瘤微环境

Bibek Bhatta, Ishai Luz, Christian Krueger, Fanny Xueting Teo, David P Lane, Kanaga Sabapathy, Tomer Cooks

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

突变 p53 癌症通过外泌体 miR-1246 将巨噬细胞重编程为肿瘤支持巨噬细胞

Tomer Cooks, Ioannis S Pateras, Lisa M Jenkins, Keval M Patel, Ana I Robles, James Morris, Tim Forshew, Ettore Appella, Vassilis G Gorgoulis, Curtis C Harris

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

突变 p53 功能增强是结直肠癌干细胞标志物高表达水平的基础

Hilla Solomon, Nathan Dinowitz, Ioannis S Pateras, Tomer Cooks, Yoav Shetzer, Alina Molchadsky, Meital Charni, Stav Rabani, Gabriela Koifman, Ohad Tarcic, Ziv Porat, Ira Kogan-Sakin, Naomi Goldfinger, Moshe Oren, Curtis C Harris, Vassilis G Gorgoulis, Varda Rotter