日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Label-Free Screening of Drug-Induced Liver Injury Using Stimulated Raman Scattering Microscopy and Spectral Phasor Analysis

利用受激拉曼散射显微镜和光谱相量分析进行药物性肝损伤的无标记筛查

Tipping, William J; Wilson, Liam T; Tomkinson, Nicholas C O; Faulds, Karen; Graham, Duncan

A Mechanistic Investigation of the N-Hydroxyphthalimide Catalyzed Benzylic Oxidation Mediated by Sodium Chlorite

亚氯酸钠介导的N-羟基邻苯二甲酰亚胺催化苄位氧化的机理研究

Grunshaw, Thomas; Wood, Susanna H; Sproules, Stephen; Parrott, Andrew; Nordon, Alison; Shapland, Peter D P; Wheelhouse, Katherine M P; Tomkinson, Nicholas C O

Expanding the Range of Bioorthogonal Tags for Multiplex Stimulated Raman Scattering Microscopy

扩展用于多重受激拉曼散射显微镜的生物正交标签范围

Murphy, Neville; Tipping, William J; Braddick, Henry J; Wilson, Liam T; Tomkinson, Nicholas C O; Faulds, Karen; Graham, Duncan; Farràs, Pau

Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments

利用硫(VI)氟化物反应片段进行高效配体发现

Aatkar, Arron; Vuorinen, Aini; Longfield, Oliver E; Gilbert, Katharine; Peltier-Heap, Rachel; Wagner, Craig D; Zappacosta, Francesca; Rittinger, Katrin; Chung, Chun-Wa; House, David; Tomkinson, Nicholas C O; Bush, Jacob T

Peracid Oxidation of Unactivated sp(3) C-H Bonds: An Important Solvent Effect

过酸氧化未活化的sp³C-H键:重要的溶剂效应

Maciuk, Sergej; Wood, Susanna H; Patel, Vipulkumar K; Shapland, Peter D P; Tomkinson, Nicholas C O

Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry

利用直接生物学、高通量化学方法靶向羧酸残基的反应性片段

Thomas, Ross P; Grant, Emma K; Dickinson, Eleanor R; Zappacosta, Francesca; Edwards, Lee J; Hann, Michael M; House, David; Tomkinson, Nicholas C O; Bush, Jacob T

Covalent targeting of non-cysteine residues in PI4KIIIβ

PI4KIIIβ中非半胱氨酸残基的共价靶向

Cosgrove, Brett; Grant, Emma K; Bertrand, Sophie; Down, Kenneth D; Somers, Don O; P Evans, John; Tomkinson, Nicholas C O; Barker, Michael D

Temporal imaging of drug dynamics in live cells using stimulated Raman scattering microscopy and a perfusion cell culture system

利用受激拉曼散射显微镜和灌注细胞培养系统对活细胞内药物动力学进行时间成像

Tipping, William J; Merchant, Andrew S; Fearon, Rebecca; Tomkinson, Nicholas C O; Faulds, Karen; Graham, Duncan

A direct-to-biology high-throughput chemistry approach to reactive fragment screening

一种直接应用于生物体的高通量化学方法,用于反应片段筛选

Thomas, Ross P; Heap, Rachel E; Zappacosta, Francesca; Grant, Emma K; Pogány, Peter; Besley, Stephen; Fallon, David J; Hann, Michael M; House, David; Tomkinson, Nicholas C O; Bush, Jacob T

Alkene Syn- and Anti-Oxyamination with Malonoyl Peroxides

利用丙二酰过氧化物进行烯烃的顺式和反式氧化反应

Curle, Jonathan M; Perieteanu, Marina C; Humphreys, Philip G; Kennedy, Alan R; Tomkinson, Nicholas C O