Tomohide相关文献与解析，生知库 | 链接生命科学的每一步

Carbonic anhydrase 9 as a circulating biomarker and therapeutic target in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab

碳酸酐酶 9 作为循环生物标志物和治疗靶点在接受阿特珠单抗联合贝伐珠单抗治疗的肝细胞癌患者中的应用

doi:10.1136/jitc-2025-013384

Sato, Yu; Kodama, Takahiro; Maesaka, Kazuki; Kai, Machiko; Murai, Kazuhiro; Tahata, Yuki; Saito, Yoshinobu; Nakabori, Tasuku; Ohkawa, Kazuyoshi; Tanaka, Satoshi; Sakamori, Ryotaro; Miyazaki, Masanori; Furuta, Kunimaro; Ishida, Hisashi; Matsumoto, Kengo; Tawara, Seiichi; Yakushijin, Takayuki; Nozaki, Yasutoshi; Hosui, Atsushi; Nishio, Akira; Tatsumi, Nobuyuki; Kakita, Naruyasu; Yoo, Changhoon; Fukai, Moto; Taketomi, Akinobu; Hikita, Hayato; Tatsumi, Tomohide; Takehara, Tetsuo

Systemic immune profiling uncovers divergent mechanisms and predictive biomarkers of response to combination immunotherapies in hepatocellular carcinoma.

系统性免疫分析揭示了肝细胞癌联合免疫疗法反应的不同机制和预测性生物标志物。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2025-013648

Nishio Akira, Kodama Takahiro, Daiku Kazuma, Maesaka Kazuki, Tanaka Satoshi, Nozaki Yasutoshi, Kurahashi Tomohide, Matsumoto Kengo, Nawa Takatoshi, Tawara Seiichi, Tokuda Yuki, Nakabori Tasuku, Sakamori Ryotaro, Ohkawa Kazuyoshi, Miyazaki Masanori, Yamamoto Shuhei, Shigeno Satoshi, Myojin Yuta, Tahata Yuki, Hikita Hayato, Takehara Tetsuo

Liver Sinusoidal Endothelial Cells Promote Metabolic Dysfunction-associated Steatohepatitis Progression via Interleukin-1R1-mediated Chemokine Production Induced by Macrophage-derived Interleukin-1Î².

肝窦内皮细胞通过巨噬细胞衍生的白细胞介素-1β诱导的白细胞介素-1R1介导的趋化因子产生，促进代谢功能障碍相关的脂肪性肝炎进展。

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2025.101698

Fukumoto Kenji, Hikita Hayato, Saito Yoshinobu, Makino Yuki, Soma Kazumasa, Kato Seiya, Sasaki Yoichi, Myojin Yuta, Sato Katsuhiko, Sakane Sadatsugu, Murai Kazuhiro, Tahata Yuki, Kodama Takahiro, Tatsumi Tomohide, Motooka Daisuke, Kubota Yoshiaki, Kobayashi Shogo, Eguchi Hidetoshi, Takehara Tetsuo

Four-Year Outcomes for Nivolumab With Chemotherapy and Bevacizumab in Patients With Nonsquamous NSCLC in the TASUKI-52

TASUKI-52研究中，纳武利尤单抗联合化疗和贝伐单抗治疗非鳞状非小细胞肺癌患者的四年疗效

期刊:Cancer Science

影响因子:4.3

doi:10.1111/cas.70330

Lee, Jong-Seok; Sugawara, Shunichi; Kang, Jin-Hyoung; Kim, Hye Ryun; Inui, Naoki; Hida, Toyoaki; Lee, Ki Hyeong; Yoshida, Tatsuya; Tanaka, Hiroshi; Yang, Cheng-Ta; Inoue, Takako; Nishio, Makoto; Goto, Yasushi; Tamura, Tomohide; Yamamoto, Nobuyuki; Yu, Chong-Jen; Akamatsu, Hiroaki; Takahashi, Shigeru; Nakagawa, Kazuhiko

Caldesmon-1-mediated actin dynamics is essential for osteogenic differentiation of aortic valve interstitial cells.

钙调蛋白-1介导的肌动蛋白动力学对于主动脉瓣间质细胞的成骨分化至关重要。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-39938-x

Komoda Munenori, Sakaue Tomohisa, Nakao Yasuhisa, Sakamoto Hiroshi, Fukunishi Takuma, Higaki Tomohide, Aono Jun, Kurobe Hirotsugu, Kurata Mie, Nishimura Takashi, Izutani Hironori

细胞生物学

发表日期：2026

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Plain language summary of TASUKI-52: A study looking at nivolumab plus platinum chemotherapy and bevacizumab as a combined treatment for people with advanced or recurrent nonsquamous non-small cell lung cancer (NSCLC)

TASUKI-52 简明语言摘要：一项研究，旨在探讨纳武利尤单抗联合铂类化疗和贝伐单抗作为治疗晚期或复发性非鳞状非小细胞肺癌 (NSCLC) 患者的联合疗法。

期刊:Future Oncology

影响因子:2.6

doi:10.1080/14796694.2026.2617855

Sugawara, Shunichi; Lee, Jong-Seok; Kang, Jin-Hyoung; Kim, Hye Ryun; Inui, Naoki; Hida, Toyoaki; Lee, Ki Hyeong; Yoshida, Tatsuya; Tanaka, Hiroshi; Yang, Cheng-Ta; Inoue, Takako; Nishio, Makoto; Goto, Yasushi; Tamura, Tomohide; Yamamoto, Nobuyuki; Yu, Chong-Jen; Akamatsu, Hiroaki; Takahashi, Shigeru; Nakagawa, Kazuhiko

Pancreatic lymphangioma and concurrent intestinal lymphangiectasia in a dog

犬胰腺淋巴管瘤合并肠道淋巴管扩张症

期刊:Journal of Veterinary Internal Medicine

影响因子:2.2

doi:10.1093/jvimsj/aalaf033

Ishikawa, Taisuke; Kuramoto, Tomohide; Hifumi, Tatsuro; Kozuma, Chika; Kozuma, Machiko; Hirano, Keishi; Moriwaki, Erisa; Sakanoue, Shota; Miyoshi, Noriaki; Miura, Naoki; Yamato, Osamu; Takahashi, Masashi

发表日期：2026

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Near infrared ray-guided partial cystectomy using da Vinci Firefly(®) technology and intraoperative cystoscopy for urachal cyst, suspected of urachal tumor

采用达芬奇萤火虫®技术进行近红外线引导下部分膀胱切除术，并结合术中膀胱镜检查，治疗疑似脐尿管肿瘤的脐尿管囊肿。

期刊:Investigative and Clinical Urology

影响因子:2.1

doi:10.4111/icu.20250141

Kurobe, Masahiro; Ogawa, Tomohide; Satoh, Yuya; Yamamoto, Mao; Ushijima, Kei; Okamoto, Keita; Numahata, Daisuke; Ohta, Tomoyuki; Takayama, Tatsuya

New Neuroimaging Findings in Enoyl-CoA Hydratase Short-Chain 1 (ECHS1) Deficiency

烯酰辅酶A水合酶短链1 (ECHS1) 缺乏症的新神经影像学发现

期刊:Cureus Journal of Medical Science

影响因子:1.3

doi:10.7759/cureus.102392

Tada, Hiroko; Ichimoto, Keiko; Murayama, Kei; Goto, Tomohide; Takanashi, Jun-Ichi

发表日期：2026

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Machine learning-predicted insulin resistance is a risk factor for 12 types of cancer

机器学习预测的胰岛素抵抗是12种癌症的风险因素。

Carbonic anhydrase 9 as a circulating biomarker and therapeutic target in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab

碳酸酐酶 9 作为循环生物标志物和治疗靶点在接受阿特珠单抗联合贝伐珠单抗治疗的肝细胞癌患者中的应用

Systemic immune profiling uncovers divergent mechanisms and predictive biomarkers of response to combination immunotherapies in hepatocellular carcinoma.

系统性免疫分析揭示了肝细胞癌联合免疫疗法反应的不同机制和预测性生物标志物。

Liver Sinusoidal Endothelial Cells Promote Metabolic Dysfunction-associated Steatohepatitis Progression via Interleukin-1R1-mediated Chemokine Production Induced by Macrophage-derived Interleukin-1Î².

肝窦内皮细胞通过巨噬细胞衍生的白细胞介素-1β诱导的白细胞介素-1R1介导的趋化因子产生，促进代谢功能障碍相关的脂肪性肝炎进展。

Four-Year Outcomes for Nivolumab With Chemotherapy and Bevacizumab in Patients With Nonsquamous NSCLC in the TASUKI-52

TASUKI-52研究中，纳武利尤单抗联合化疗和贝伐单抗治疗非鳞状非小细胞肺癌患者的四年疗效

Caldesmon-1-mediated actin dynamics is essential for osteogenic differentiation of aortic valve interstitial cells.

钙调蛋白-1介导的肌动蛋白动力学对于主动脉瓣间质细胞的成骨分化至关重要。

Plain language summary of TASUKI-52: A study looking at nivolumab plus platinum chemotherapy and bevacizumab as a combined treatment for people with advanced or recurrent nonsquamous non-small cell lung cancer (NSCLC)

TASUKI-52 简明语言摘要：一项研究，旨在探讨纳武利尤单抗联合铂类化疗和贝伐单抗作为治疗晚期或复发性非鳞状非小细胞肺癌 (NSCLC) 患者的联合疗法。

Pancreatic lymphangioma and concurrent intestinal lymphangiectasia in a dog

犬胰腺淋巴管瘤合并肠道淋巴管扩张症

Near infrared ray-guided partial cystectomy using da Vinci Firefly(®) technology and intraoperative cystoscopy for urachal cyst, suspected of urachal tumor

采用达芬奇萤火虫®技术进行近红外线引导下部分膀胱切除术，并结合术中膀胱镜检查，治疗疑似脐尿管肿瘤的脐尿管囊肿。

New Neuroimaging Findings in Enoyl-CoA Hydratase Short-Chain 1 (ECHS1) Deficiency

烯酰辅酶A水合酶短链1 (ECHS1) 缺乏症的新神经影像学发现