日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolomics Analyses of 14 Classical Neurotransmitters by GC-TOF with LC-MS Illustrates Secretion of 9 Cell-Cell Signaling Molecules from Sympathoadrenal Chromaffin Cells in the Presence of Lithium

利用GC-TOF-LC-MS对14种经典神经递质进行代谢组学分析,揭示了锂存在下交感肾上腺嗜铬细胞分泌9种细胞间信号分子的情况。

Hook, Vivian; Kind, Tobias; Podvin, Sonia; Palazoglu, Mine; Tran, Carol; Toneff, Thomas; Samra, Stephanie; Lietz, Christopher; Fiehn, Oliver

Profiles of secreted neuropeptides and catecholamines illustrate similarities and differences in response to stimulation by distinct secretagogues

分泌型神经肽和儿茶酚胺的分布情况表明,它们对不同促分泌剂刺激的反应既有相似之处,也有不同之处。

Podvin, Sonia; Bundey, Richard; Toneff, Thomas; Ziegler, Michael; Hook, Vivian

Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons

人类诱导多能干细胞神经元表现出活动依赖性神经递质分泌:精神分裂症神经元中儿茶酚胺水平异常

Hook, Vivian; Brennand, Kristen J; Kim, Yongsung; Toneff, Thomas; Funkelstein, Lydiane; Lee, Kelly C; Ziegler, Michael; Gage, Fred H

Pyroglutamate-amyloid-β and glutaminyl cyclase are colocalized with amyloid-β in secretory vesicles and undergo activity-dependent, regulated secretion

焦谷氨酸-β淀粉样蛋白和谷氨酰环化酶与β淀粉样蛋白共定位于分泌囊泡中,并经历活性依赖性的、受调控的分泌过程。

Cynis, Holger; Funkelstein, Lydiane; Toneff, Thomas; Mosier, Charles; Ziegler, Michael; Koch, Birgit; Demuth, Hans-Ulrich; Hook, Vivian

Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters

组织蛋白酶H在分泌囊泡中作为氨肽酶发挥作用,用于产生脑啡肽和加兰素肽类神经递质。

Lu, Weiya Douglas; Funkelstein, Lydiane; Toneff, Thomas; Reinheckel, Thomas; Peters, Christoph; Hook, Vivian

Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.

组织蛋白酶 L 在小鼠大脑皮层和垂体 AtT-20 细胞中胆囊收缩素的产生中起着重要作用:蛋白酶基因敲除和抑制剂研究

Beinfeld Margery C, Funkelstein Lydiane, Foulon Thierry, Cadel Sandrine, Kitagawa Kouki, Toneff Thomas, Reinheckel Thomas, Peters Christoph, Hook Vivian

Endopin serpin protease inhibitors localize with neuropeptides in secretory vesicles and neuroendocrine tissues

内皮素丝氨酸蛋白酶抑制剂与神经肽一起定位于分泌囊泡和神经内分泌组织中。

Hwang, Shin-Rong; Bundey, Richard; Toneff, Thomas; Hook, Vivian

Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression

组织蛋白酶L参与分泌囊泡中神经肽Y的生成,这已通过蛋白酶基因敲除和表达实验得到证实。

Funkelstein, Lydiane; Toneff, Thomas; Hwang, Shin-Rong; Reinheckel, Thomas; Peters, Christoph; Hook, Vivian

Differential activation of enkephalin, galanin, somatostatin, NPY, and VIP neuropeptide production by stimulators of protein kinases A and C in neuroendocrine chromaffin cells

神经内分泌嗜铬细胞中蛋白激酶A和C的刺激因子对脑啡肽、加兰素、生长抑素、神经肽Y和血管活性肠肽(VIP)等神经肽的产生具有差异性激活作用。

Hook, Vivian; Toneff, Thomas; Baylon, Sheley; Sei, Catherine