日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dynamics and Mechanism of Off- to On-Switching in Dreiklang a Decoupled Reversibly Switchable Fluorescent Protein

Dreiklang 解耦可逆开关荧光蛋白的关断-开启切换动力学及机制

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202518264
Fatima, Anam; He, Yongle; Rosenberger, Danielle; Greetham, Gregory M; Malakar, Partha; Lukacs, Andras; Tonge, Peter J; Meech, Stephen R
IF
发表日期：2026
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A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells.

一种用于测量细胞中 PRMT5 复合物非竞争性结合的 BRET 生物传感器。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65558-6
Rothweiler Elisabeth M, Michaud Ani, Stefaniak Jakub, Singh Usha, Mikulsky Brynwood B, Vasta James D, Beck Michael T, Wilkinson Jennifer, Ward Jennifer A, Rogers Catherine M, Balıkçı Esra, Tranberg-Jensen Jeppe, Hansen Jesper S, Loppnau Peter, Whitty Adrian, Brennan Paul E, Tonge Peter J, Robers Matthew B, Huber Kilian V M
细胞生物学
RET
发表日期：2025
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Enhancing Proton-Coupled Electron Transfer in Blue Light Using FAD Photoreceptor AppA(BLUF)

利用FAD光感受器AppA(BLUF)增强蓝光中的质子耦合电子转移

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c11817
He, YongLe; Gil, Agnieszka A; Laptenok, Sergey P; Fatima, Anam; Collado, Jinnette Tolentino; Iuliano, James N; Woroniecka, Helena A; Brust, Richard; Sabbah, Aya; Towrie, Michael; Greetham, Gregory M; Sazanovich, Igor V; French, Jarrod B; Lukacs, Andras; Meech, Stephen R; Tonge, Peter J
发表日期：2025
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Modulating the Binding Kinetics of Bruton's Tyrosine Kinase Inhibitors through Transition-State Effects

通过过渡态效应调节布鲁顿酪氨酸激酶抑制剂的结合动力学

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c07063
Bravo, Eduardo Jr; Li, Yong; Lin, David Yin-Wei; Srinivasan, Bharath; Barone, Marco; Li, Stan Xiaogang; DelloRusso, Francesca; Rahiyanath, Anza Suneer; Corrionero, Ana; Alfonso, Patricia; Prendiville, Niall; Kozakov, Dima; Andreotti, Amy H; Tonge, Peter J
信号转导
发表日期：2025
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Ultrafast photophysics of a positive reversibly switchable fluorescent protein

正可逆开关荧光蛋白的超快光物理特性

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc04491j
Fatima, Anam; He, YongLe; Iuliano, James N; Greetham, Gregory M; Malakar, Partha; Hall, Christopher; Woroniecka, Helena A; Richardson, Brian C; French, Jarrod B; Lukacs, Andras; Tonge, Peter J; Meech, Stephen R
IF
发表日期：2025
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Selectivity of the Time-Dependent M. tuberculosis LeuRS Inhibitor Ganfeborole Is Driven by Target Vulnerability

时间依赖性结核分枝杆菌亮氨酸合成酶抑制剂甘非硼罗的选择性受靶标脆弱性驱动

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5c00705
Wang, Mingqian; He, YongLe; Cohen, Siobhan A; Strohm, Amanda R; Shetye, Gauri; Franzblau, Scott G; Walker, Stephen G; Alley, M R K; Tonge, Peter J
发表日期：2025
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Identifying Modulators of the Post-Antibiotic Effect

识别抗生素后效应的调节因子

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.5c00424
Gilberti, Alexa L; Tu, Megan M; Rachwalski, Kenneth; Ali, Madeeha I; Cohen, Siobhan A; Akoglu, Melike; Pollard-Kerning, Alyssa C; Tolentino Collado, Jinnette; Sabbah, Aya; Abou Said, Franchesca; Dela, Purnima; Walker, Stephen G; Haley, John D; Brown, Eric D; Tonge, Peter J
发表日期：2025
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Probing the Signal Transduction Mechanism of the Light-Activated Adenylate Cyclase OaPAC Using Unnatural Amino Acid Mutagenesis

利用非天然氨基酸诱变技术探究光激活腺苷酸环化酶OaPAC的信号转导机制

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.4c00627
Jewlikar, Samruddhi S; Tolentino Collado, Jinnette; Ali, Madeeha I; Sabbah, Aya; He, YongLe; Iuliano, James N; Hall, Christopher R; Adamczyk, Katrin; Greetham, Gregory M; Lukacs, Andras; Meech, Stephen R; Tonge, Peter J
信号转导
发表日期：2025
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Time-Dependent Inhibition of Leucyl-tRNA-Synthetase (LeuRS): Insight into Target Vulnerability

亮氨酰tRNA合成酶（LeuRS）的时间依赖性抑制：对靶标脆弱性的深入了解

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.4c01017
Wang, Mingqian; He, YongLe; Cohen, Siobhan A; Strohm, Amanda R; Haley, John D; Walker, Stephen G; Alley, M R K; Tonge, Peter J
发表日期：2025
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An Assessment of Kinase Selectivity, Enzyme Inhibition Kinetics and in Vitro Activity for Several Bruton Tyrosine Kinase (BTK) Inhibitors

对几种布鲁顿酪氨酸激酶（BTK）抑制剂的激酶选择性、酶抑制动力学和体外活性进行评估

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00412
Corrionero, Ana; Zhang, Xiaohu; Alfonso, Patricia; Morris, Patrick J; Klumpp-Thomas, Carleen; Melani, Christopher; McKnight, Crystal; Phelan, James D; Holland, David; Wilson, Kelli; Hoyt, Scott B; Roschewski, Mark; Tonge, Peter J; Wilson, Wyndham; Ceribelli, Michele; Staudt, Louis M; Thomas, Craig J
BTK
信号转导
发表日期：2025
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