日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PTP1B inhibition promotes microglial phagocytosis in Alzheimer's disease models by enhancing SYK signaling

PTP1B抑制通过增强SYK信号传导促进阿尔茨海默病模型中的小胶质细胞吞噬作用

Cen, Yuxin; R Alves, Steven; Song, Dongyan; Felice, Christy; Preall, Jonathan B; Van Aelst, Linda; Tonks, Nicholas K

Identification and Validation of an Inhibitor of the Protein Kinases PIM and DYRK.

鉴定和验证蛋白激酶 PIM 和 DYRK 的抑制剂。

Bencze Gyula, Venkataramani Prabhadevi, Elkayam Elad, Rivera Keith D, Garg Ankur, Szabadakai Istvan, Orfi Laszlo, Joshua-Tor Leemor, Pappin Darryl J, Tonks Nicholas K

The dual-specificity phosphatase JSP1 regulates neutrophil adhesion via integrin-SRC signaling in vascular inflammation

双特异性磷酸酶JSP1通过整合素-SRC信号通路调节血管炎症中的中性粒细胞黏附。

Li, Li; Tonks, Nicholas K

Ganaxolone, an approved therapy for CDKL5-Deficiency Disorder, is an inhibitor of PTP1B

加那索隆(Ganaxolone)是一种获批用于治疗 CDKL5 缺乏症的药物,它是 PTP1B 的抑制剂。

Zubiete-Franco, Imanol; Hu, Qingting; Tonks, Nicholas K

JSP1 Regulates Neutrophil Adhesion via Integrin-SRC Signaling in Vascular Inflammation

JSP1通过整合素-SRC信号通路调节血管炎症中的中性粒细胞黏附

Li, Li; Tonks, Nicholas K

Identification and Validation of an inhibitor of the protein kinases PIM and DYRK

鉴定和验证蛋白激酶 PIM 和 DYRK 的抑制剂

Bencze, Gyula; Venkataramani, Prabhadevi; Elkayam, Elad; Rivera, Keith D; Garg, Ankur; Szabadkai, Istvan; Orfi, Laszlo; Joshua-Tor, Leemor; Pappin, Darryl; Tonks, Nicholas K

Novel small-molecule inhibitors of the protein kinase DYRK: Potential therapeutic candidates in cancer

新型小分子蛋白激酶DYRK抑制剂:癌症治疗的潜在候选药物

Venkataramani, Prabhadevi; Elkayam, Elad; Garg, Ankur; Cheng, Kai Fan; Altiti, Ahmad; He, Mingzhu; Thakur, Khushabu; Michalopoulou, Evdokia; Gonzalez, Camila; Felice, Christy; Van-Aelst, Linda; Pappin, Darryl; Joshua-Tor, Leemor; Al-Abed, Yousef; Tonks, Nicholas K

Famotidine increases cellular phospho-tyrosine levels.

法莫替丁可提高细胞内磷酸酪氨酸水平

Zubiete-Franco Imanol, Tonks Nicholas K

Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow

蛋白质酪氨酸磷酸酶:参天大树源于小小的橡子

Tonks, Nicholas K

Connecting copper and cancer: from transition metal signalling to metalloplasia

铜与癌症的联系:从过渡金属信号传导到金属增生

Ge, Eva J; Bush, Ashley I; Casini, Angela; Cobine, Paul A; Cross, Justin R; DeNicola, Gina M; Dou, Q Ping; Franz, Katherine J; Gohil, Vishal M; Gupta, Sanjeev; Kaler, Stephen G; Lutsenko, Svetlana; Mittal, Vivek; Petris, Michael J; Polishchuk, Roman; Ralle, Martina; Schilsky, Michael L; Tonks, Nicholas K; Vahdat, Linda T; Van Aelst, Linda; Xi, Dan; Yuan, Peng; Brady, Donita C; Chang, Christopher J