日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunodominant antiviral T cell responses outcompete immuno-subdominant antitumor responses to reduce the efficacy of oncolytic viroimmunotherapy.

免疫优势的抗病毒 T 细胞反应会抑制免疫劣势的抗肿瘤反应,从而降低溶瘤病毒免疫疗法的疗效

Vile Richard, Kendall Benjamin, Liseth Olivia, Sangsuwannukul Thanich, Elliott Natalie, Yerovi Maria Chiriboga, Thompson Jill, Swanson Jack, Rizk Soha, Diaz Rosa, Tonne Jason

A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses

一项I期溶瘤病毒试验,采用表达人干扰素β和酪氨酸酶相关蛋白1的水疱性口炎病毒,通过瘤内注射和静脉注射治疗葡萄膜黑色素瘤:安全性、有效性和T细胞反应

Smith, Katherine E R; Peng, Kah-Whye; Pulido, Jose S; Weisbrod, Adam J; Strand, Carrie A; Allred, Jacob B; Newsom, Alysha N; Zhang, Lianwen; Packiriswamy, Nandakumar; Kottke, Timothy; Tonne, Jason M; Moore, Madelyn; Montane, Heather N; Kottschade, Lisa A; McWilliams, Robert R; Dudek, Arkadiusz Z; Yan, Yiyi; Dimou, Anastasios; Markovic, Svetomir N; Federspiel, Mark J; Vile, Richard G; Dronca, Roxana S; Block, Matthew S

Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors

Ad-CD40L 可动员 CD4 T 细胞用于治疗脑干肿瘤

Wongthida, Phonphimon; Schuelke, Matthew R; Driscoll, Christopher B; Kottke, Timothy; Thompson, Jill M; Tonne, Jason; Stone, Cathy; Huff, Amanda L; Wetmore, Cynthia; Davies, James A; Parker, Alan L; Evgin, Laura; Vile, Richard G

Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients

在移植到糖尿病受体之前,靶向诱导产生器官型葡萄糖和GLP-1反应性β细胞

Zhu, Yaxi; Tonne, Jason M; Liu, Qian; Schreiber, Claire A; Zhou, Zhiguang; Rakshit, Kuntol; Matveyenko, Aleksey V; Terzic, Andre; Wigle, Dennis; Kudva, Yogish C; Ikeda, Yasuhiro

Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes

饮食诱导糖尿病的潜在机制:β细胞葡萄糖激酶功能受损

Lu, Brian; Kurmi, Kiran; Munoz-Gomez, Miguel; Jacobus Ambuludi, Egon J; Tonne, Jason M; Rakshit, Kuntol; Hitosugi, Taro; Kudva, Yogish C; Matveyenko, Aleksey V; Ikeda, Yasuhiro

Divergent susceptibilities to AAV-SaCas9-gRNA vector-mediated genome-editing in a single-cell-derived cell population

单细胞衍生细胞群对AAV-SaCas9-gRNA载体介导的基因组编辑的敏感性存在差异

Morsy, Salma G; Tonne, Jason M; Zhu, Yaxi; Lu, Brian; Budzik, Karol; Krempski, James W; Ali, Sherine A; El-Feky, Mohamed A; Ikeda, Yasuhiro

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue

运动可预防饮食诱导的脂肪组织细胞衰老

Schafer, Marissa J; White, Thomas A; Evans, Glenda; Tonne, Jason M; Verzosa, Grace C; Stout, Michael B; Mazula, Daniel L; Palmer, Allyson K; Baker, Darren J; Jensen, Michael D; Torbenson, Michael S; Miller, Jordan D; Ikeda, Yasuhiro; Tchkonia, Tamara; van Deursen, Jan M; Kirkland, James L; LeBrasseur, Nathan K

Beta cell regeneration after single-round immunological destruction in a mouse model

小鼠模型中单轮免疫破坏后β细胞的再生

Tonne, Jason M; Sakuma, Toshie; Munoz-Gomez, Miguel; El Khatib, Moustafa; Barry, Michael A; Kudva, Yogish C; Ikeda, Yasuhiro

Cardiac BNP gene delivery prolongs survival in aged spontaneously hypertensive rats with overt hypertensive heart disease

心脏BNP基因导入可延长老年自发性高血压伴明显高血压性心脏病大鼠的生存期

Tonne, Jason M; Holditch, Sara J; Oehler, Elise A; Schreiber, Claire A; Ikeda, Yasuhiro; Cataliotti, Alessandro

No evidence of XMRV in prostate cancer cohorts in the Midwestern United States

美国中西部前列腺癌患者队列中未发现XMRV病毒感染的证据

Sakuma, Toshie; Hué, Stéphane; Squillace, Karen A; Tonne, Jason M; Blackburn, Patrick R; Ohmine, Seiga; Thatava, Tayaramma; Towers, Greg J; Ikeda, Yasuhiro