日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa

毛囊干细胞命运支持化脓性汗腺炎的不同临床内型

Onfroy, Audrey; Jean-Louis, Francette; Le Corvoisier, Philippe; Coulpier, Fanny; Muret, Kévin; Bonnet, Eric; Arrouasse, Raphaele; Boucle, Caroline; Abid, Salwa; Sbidian, Emilie; Bergqvist, Christina; Wolkenstein, Pierre; Godot, Véronique; Deleuze, Jean-François; Lévy, Yves; Topilko, Piotr; Audureau, Etienne; Hue, Sophie

Pharmacological inhibition of RAS pathway alleviates spine deformity in a mouse model of neurofibromatosis type 1.

RAS 通路的药理学抑制可减轻 1 型神经纤维瘤病小鼠模型的脊柱畸形。

Kovaci Franceska, Goachet Cassandre, Perrin Simon, Slimani Lotfi, Coulpier Fanny, Tilotta Françoise, Topilko Piotr, Colnot Céline

Glial-to-mesenchymal transition of tumor Schwann cells drives the genetic burden in MPNSTs from neurofibromatosis type 1 mouse model.

神经纤维瘤病 1 型小鼠模型中,肿瘤雪旺细胞的胶质细胞向间质细胞的转化驱动了 MPNST 的遗传负担。

Radomska Katarzyna J, Onfroy Audrey, Lecerf Laure, Job Bastien, Beaude Aurélien, Sanz Laura Sesma, El Jalkh Tatiana, Thieffry Denis, Charnay Patrick, Wolkenstein Pierre, Ortonne Nicolas, Coulpier Fanny, Topilko Piotr

Glia at Transition Zones

过渡区的神经胶质细胞

Kucenas, Sarah; Pulh, Pernelle; Topilko, Piotr; Smith, Cody J

Unraveling the development of cutaneous neurofibromas in neurofibromatosis type 1

揭示1型神经纤维瘤病中皮肤神经纤维瘤的发生发展机制

Pernelle Pulh ,Fanny Coulpier ,Audrey Onfroy ,Layna Oubrou ,Wanzhen Zhang ,Léa Toledano ,Elie Abou Zougheib ,Laura Fertitta ,Pierre Wolkenstein ,Piotr Topilko

Organization and development of bilateral somatosensory feedback projections in mice

小鼠双侧体感反馈投射的组织和发育

Grace Houser ,Alba Vieites Prado ,Thomas Topilko ,Clara Nguyen ,Patricia Gaspar ,Nicolas Renier

Transient nicotine exposure in early adolescent male mice freezes their dopamine circuits in an immature state

青春期早期雄性小鼠短暂接触尼古丁会导致其多巴胺回路处于未成熟状态

Lauren M Reynolds, Aylin Gulmez, Sophie L Fayad, Renan Costa Campos, Daiana Rigoni, Claire Nguyen, Tinaïg Le Borgne, Thomas Topilko, Domitille Rajot, Clara Franco, Sebastian P Fernandez, Fabio Marti, Nicolas Heck, Alexandre Mourot, Nicolas Renier, Jacques Barik, Philippe Faure

Motor innervation directs the correct development of the mouse sympathetic nervous system

运动神经支配指导小鼠交感神经系统的正确发育

Alek G Erickson #, Alessia Motta #, Maria Eleni Kastriti, Steven Edwards, Fanny Coulpier, Emy Théoulle, Aliia Murtazina, Irina Poverennaya, Daniel Wies, Jeremy Ganofsky, Giovanni Canu, Francois Lallemend, Piotr Topilko, Saida Hadjab, Kaj Fried, Christiana Ruhrberg, Quenten Schwarz, Valerie Castellan

MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells

MEK-SHP2抑制剂可预防由雪旺细胞和骨骼干/祖细胞中NF1缺失引起的胫骨假关节形成。

Perrin, Simon; Protic, Sanela; Bretegnier, Vincent; Laurendeau, Ingrid; de Lageneste, Oriane Duchamp; Panara, Nicolas; Ruckebusch, Odile; Luka, Marine; Masson, Cécile; Maillard, Théodora; Coulpier, Fanny; Pannier, Stéphanie; Wicart, Philippe; Hadj-Rabia, Smail; Radomska, Katarzyna J; Zarhrate, Mohammed; Ménager, Mickael; Vidaud, Dominique; Topilko, Piotr; Parfait, Béatrice; Colnot, Céline

Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment

针对突触后谷氨酸受体支架蛋白 PSD-95 和 PICK1 治疗肥胖症

Nicole Fadahunsi, Jonas Petersen, Sophia Metz, Alexander Jakobsen, Cecilie Vad Mathiesen, Alberte Silke Buch-Rasmussen, Nigel Kurgan, Jeppe Kjærgaard Larsen, Rita C Andersen, Thomas Topilko, Charlotte Svendsen, Mia Apuschkin, Grethe Skovbjerg, Jan Hendrik Schmidt, Grace Houser, Sara Elgaard Jager, A