日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.

早期自噬蛋白 ATG13 的基因缺失会损害线粒体能量代谢,增强氧化应激,诱导巨噬细胞极化为 M1 炎症模式,并损害骨骼肌中的髓鞘完整性。

Toriola Mubaraq A, Timlin Emma, Bulbule Sarojini, Reyes Amy, Adedeji Omolola Mary, Gottschalk C Gunnar, Barua Animesh, Arnold Leggy A, Roy Avik

Development of novel alpha 2B adrenergic receptor ligands by using a palladium catalyzed Buchwald Hartwig amination with a brominated benzodiazepine

利用钯催化的Buchwald-Hartwig胺化反应,以溴代苯二氮卓类化合物为原料,开发新型α2B肾上腺素能受体配体。

Fernando, Maya R T; Vincent, Alexander B; Harrington, Shaun G; Toriola, Mubaraq A; Medubi, Kayode M; Meyer, Michelle J; Webb, Daniel A; Arnold, Leggy A

Development of novel pegylated imidazobenzodiazepines as inhaled asthma drug candidates

开发新型聚乙二醇化咪唑并苯二氮卓类化合物作为吸入性哮喘候选药物

Kowalczyk, Ethan T; Medubi, Kayode M; Meyer, Michelle J; Toriola, Mubaraq A; Haasch, Tyler J; Vesperman, Makena R; Webb, Daniel A; Stafford, Douglas C; Yocum, Gene T; Emala, Charles W; Arnold, Leggy A

Genetic depletion of early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.

早期自噬蛋白 ATG13 的基因缺失会损害线粒体能量代谢,增强氧化应激,诱导巨噬细胞极化为 M1 炎症模式,并损害骨骼肌中的髓鞘完整性

Toriola Mubaraq A, Timlin Emma, Bulbule Sarojini, Reyes Amy, Adedeji Omolola Mary, Gottschalk C Gunnar, Barua Animesh, Arnold Leggy A, Roy Avik