日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors

Gs蛋白偶联受体下游Ca2+信号多样化的分子机制

Julian Brands # ,Sergi Bravo # ,Lars Jürgenliemke # ,Lukas Grätz ,Hannes Schihada ,Fabian Frechen ,Judith Alenfelder ,Cy Pfeil ,Paul Georg Ohse ,Suzune Hiratsuka ,Kouki Kawakami ,Luna C Schmacke ,Nina Heycke ,Asuka Inoue ,Gabriele König ,Alexander Pfeifer ,Dagmar Wachten ,Gunnar Schulte ,Torsten Steinmetzer ,Val J Watts ,Jesús Gomeza ,Katharina Simon ,Evi Kostenis

ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells

ACE2 是 TMPRSS2 催化的呼吸道细胞中甲型流感病毒蛋白水解激活的新型调节剂

Miriam Ruth Heindl, Anna-Lena Rupp, Marie Schwerdtner, Dorothea Bestle, Anne Harbig, Amy De Rocher, Luna C Schmacke, Bart Staker, Torsten Steinmetzer, David A Stein, Hong M Moulton, Eva Böttcher-Friebertshäuser

Unveiling the Role of TMPRSS2 in the Proteolytic Activation of Pandemic and Zoonotic Influenza Viruses and Coronaviruses in Human Airway Cells

揭示 TMPRSS2 在人类呼吸道细胞中对大流行性和人畜共患流感病毒及冠状病毒的蛋白水解激活中的作用

Marie Schwerdtner, Luna C Schmacke, Julia Nave, Hannah Limburg, Torsten Steinmetzer, David A Stein, Hong M Moulton, Eva Böttcher-Friebertshäuser

Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage

TMPRSS2 和组织蛋白酶 L 在未知位置对埃博拉病毒糖蛋白 GP 进行新的蛋白水解激活,可以补偿弗林蛋白酶的裂解

Dorothea Bestle, Linda Bittel, Anke-Dorothee Werner, Lennart Kämper, Olga Dolnik, Verena Krähling, Torsten Steinmetzer, Eva Böttcher-Friebertshäuser

Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease

硼亮氨酸衍生的寨卡病毒蛋白酶共价抑制剂

Niklas J Braun, Simon Huber, Luna C Schmacke, Andreas Heine, Torsten Steinmetzer

Transfer mechanism of cell-free synthesized membrane proteins into mammalian cells

无细胞合成膜蛋白向哺乳动物细胞的转移机制

Simon Umbach, Roman Levin, Sebastian Neumann, Torsten Steinmetzer, Volker Dötsch, Frank Bernhard

Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect

人类肠上皮细胞和原代人肝细胞暴露于胰蛋白酶样丝氨酸蛋白酶抑制剂具有潜在的抗病毒作用

Erzsébet Pászti-Gere, Judit Pomothy, Ákos Jerzsele, Oliver Pilgram, Torsten Steinmetzer

RNase P Inhibitors Identified as Aggregators

RNase P 抑制剂被鉴定为聚集剂

Isabell Schencking, Eva M Schäfer, J H William Scanlan, Benjamin M Wenzel, Rolf E Emmerich, Torsten Steinmetzer, Wibke E Diederich, Martin Schlitzer, Roland K Hartmann

OFF-State-Specific Inhibition of the Proprotein Convertase Furin

OFF 状态特异性抑制前蛋白转化酶弗林蛋白酶

Sven O Dahms, Tanja Haider, Gerhard Klebe, Torsten Steinmetzer, Hans Brandstetter

Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways

转录组分析和蛋白酶抑制实验确定了在小鼠呼吸道中激活 H3N2 甲型流感病毒和乙型流感病毒的蛋白酶

Anne Harbig, Marco Mernberger, Linda Bittel, Stephan Pleschka, Klaus Schughart, Torsten Steinmetzer, Thorsten Stiewe, Andrea Nist, Eva Böttcher-Friebertshäuser