日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De novo antibody identification in human blood from full-length single B cell transcriptomics and matching haplotype-resolved germline assemblies

利用全长单B细胞转录组学和匹配的单倍型解析的种系组装,从头鉴定人血中的抗体。

Beaulaurier, John; Ly, Lynn; Duty, J Andrew; Tyer, Carly; Stevens, Christian; Hung, Chuan-Tien; Sookdeo, Akash; Drong, Alex W; Kowdle, Shreyas; Guzman-Solis, Axel; Tortorella, Domenico; Turner, Daniel J; Juul, Sissel; Hickey, Scott; Lee, Benhur

Broadly neutralizing human monoclonal antibodies against BK polyomavirus genotypes

针对BK多瘤病毒基因型的广谱中和人单克隆抗体

Duty, J Andrew; Kraus, Thomas A; Kumar, Madhu; Tortorella, Nicolo A; Jimoh, Tajudeen O; Barrall, Emma B; Pastrana, Diana V; Buck, Christopher B; Moran, Thomas M; Tortorella, Domenico

Characterization of human cytomegalovirus infection dynamics in human microglia.

人类巨细胞病毒感染人类小胶质细胞动力学的特征分析

Nuevalos Guaita Marcos, Jimoh Tajudeen O, Barrall Emma B, Atanasoff Kristina E, Ehrlich Michelle E, Gandy Sam, García-Ríos Estéfani, Perez Romero Pilar, Duty J Andrew, Tortorella Domenico

Precision engineering of human cytomegalovirus without BAC constraints: a Sendai virus-delivered CRISPR/Cas9 approach.

无需 BAC 限制即可对人类巨细胞病毒进行精确工程改造:一种利用仙台病毒递送的 CRISPR/Cas9 方法

Carmichael Jillian C, Stevens Christian S, Atanasoff Kristina E, Kowdle Shreyas, Reis Rebecca A, Tortorella Domenico, Lee Benhur

N-arylpyrimidinamine (NAPA) compounds are broadly acting inhibitors of human cytomegalovirus infection and spread

N-芳基嘧啶胺(NAPA)化合物是广谱的人类巨细胞病毒感染和传播抑制剂。

Atanasoff, Kristina E; Ophir, Sabrina I; Parsons, Andrea J; Paredes Casado, Jailene; Lurain, Nell S; Bowlin, Terry L; Opperman, Timothy J; Tortorella, Domenico

Heterologous immunization strategy developed broadly reactive human monoclonal antibodies against the BK virus

采用异源免疫策略,研制出针对BK病毒的广谱反应性人单克隆抗体。

Duty, J Andrew; Kraus, Thomas; Kumar, Madhu; Tortorella, Nicolo A; Jimoh, Tajudeen O; Pastrana, Diana V; Buck, Christopher B; Moran, Thomas; Tortorella, Domenico

Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.

利用小分子和病毒RNA模拟物促进的靶向蛋白质降解,生成宿主导向和病毒特异性抗病毒药物

Zhao Nan, Ho Jessica Sook Yuin, Meng Fanye, Zheng Simin, Kurland Andrew P, Tian Lu, Rea-Moreno Martha, Song Xiangyang, Seo Ji-Seon, Kaniskan H Ümit, Te Velthuis Aartjan J W, Tortorella Domenico, Chen Ya-Wen, Johnson Jeffrey R, Jin Jian, Marazzi Ivan

The CD46 ectodomain participates in human cytomegalovirus infection of epithelial cells

CD46胞外结构域参与人巨细胞病毒对上皮细胞的感染。

Parsons, Andrea J; Stein, Kathryn R; Atanasoff, Kristina E; Ophir, Sabrina I; Casado, Jailene Paredes; Tortorella, Domenico

An in vitro experimental pipeline to characterize the binding specificity of SARS-CoV-2 neutralizing antibodies

用于表征SARS-CoV-2中和抗体结合特异性的体外实验流程

Atanasoff, Kristina E; Brambilla, Luca; Adelsberg, Daniel C; Kowdle, Shreyas; Stevens, Christian S; Hung, Chuan-Tien; Fu, Yanwen; Lim, Reyna; Tran, Linh; Allen, Robert; Andrew Duty, J; Bajic, Goran; Lee, Benhur; Tortorella, Domenico

An Influenza Virus Hemagglutinin-Based Vaccine Platform Enables the Generation of Epitope Specific Human Cytomegalovirus Antibodies

基于流感病毒血凝素的疫苗平台能够产生表位特异性人巨细胞病毒抗体

Behzadi, Mohammad Amin; Stein, Kathryn R; Bermúdez-González, Maria Carolina; Simon, Viviana; Nachbagauer, Raffael; Tortorella, Domenico