日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

MiR-378 mediates the ovariectomy induced bone loss via exaggerating osteoclastogenesis and transforming growth factor beta impaired osteogenesis.

miR-378 通过加剧破骨细胞生成和转化生长因子β损害成骨作用来介导卵巢切除术引起的骨丢失。

期刊:Genes and Diseases
影响因子:9.4
doi:10.1016/j.gendis.2025.101754
Feng Lu, Yang Zhengmeng, Hou Nan, Wang Haixing, Bai Shanshan, Lu Xuan, Wang Yaofeng, Lin Sien, Tortorella Micky D, Li Gang
细胞生物学
发表日期：2026
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Entorhinal Cholecystokinin in Alzheimer's Disease: Its Earliest Vulnerability and Rescue Effects Across Different Disease Stages in a Mouse Model

内嗅皮层胆囊收缩素在阿尔茨海默病中的作用：小鼠模型中其在疾病不同阶段的早期脆弱性和拯救效应

期刊:Cellular and Molecular Neurobiology
影响因子:4.8
doi:10.1007/s10571-026-01689-8
Sui, Yixuan; Zhang, Nan; Chen, Xi; Tortorella, Micky D; He, Jufang
阿尔茨海默症
Mouse
发表日期：2026
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Cryo-EM structure of TMEM164 reveals distinct phospholipid remodeling mechanisms with anti-ferroptotic potential.

TMEM164 的冷冻电镜结构揭示了具有抗铁死亡潜力的独特磷脂重塑机制。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67651-2
Ke Minjing, Shan Yuanyue, Zhai Ziwei, Yao Guoqiang, Guo Xinyi, Li Xiaoxi, Wu Zichao, Chen Huifeng, Zhang Mengmeng, Chen Meiyu, Li Ying, Zhao Chengchen, Wang Bo, Tortorella Micky D, Shu Xiaodong, Zhang Mingfeng, Kuang Junqi, Pei Duanqing
铁死亡
发表日期：2025
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A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats.

一种新型颅骨运输技术可修复颅骨缺损，并最大限度地减少创伤性脑损伤大鼠的脑损伤后果

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202504467
Bai Shanshan, Lu Xuan, Yan Xu, Su Han, Lin Yuejun, Jiang Zhaowei, Zong Zhixian, Wang Haixing, Yan Leo Yik Chun, Zhang Xiaoting, Wang Ming, Yang Zhengmeng, Jin Jiakang, Wang Yaofeng, Lee Wayne Yuk-Wai, Jiang Xiaohua, Ko Ho, Feng Lu, Tortorella Micky D, Lin Sien, Li Gang
骨科研究
Rat
发表日期：2025
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Staphylococcal enterotoxin C2 rescued simulated microgravity-induced bone loss and the trans-differentiation of BMSCs into adipocytes.

葡萄球菌肠毒素 C2 可挽救模拟微重力引起的骨质流失，并促进 BMSC 向脂肪细胞的转分化。

期刊:NPJ Microgravity
影响因子:4.1
doi:10.1038/s41526-025-00548-y
Hou Nan, Yang Zhengmeng, Wang Haixing, Lu Xuan, Bai Shanshan, Wang Yaofeng, Lin Sien, Tortorella Micky D, Feng Lu, Li Gang
细胞生物学
发表日期：2025
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Low-Dose Staphylococcal Enterotoxin C2 Mutant Maintains Bone Homeostasis via Regulating Crosstalk between Bone Formation and Host T-Cell Effector Immunity

低剂量葡萄球菌肠毒素C2突变体通过调节骨形成与宿主T细胞效应免疫之间的相互作用来维持骨稳态

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202300989
Wang, Haixing; Lin, Sien; Feng, Lu; Huang, Baozhen; Lu, Xuan; Yang, Zhengmeng; Jiang, Zhaowei; Li, Yu-Cong; Zhang, Xiaoting; Wang, Ming; Wang, Bin; Kong, Lingchi; Pan, Qi; Bai, Shanshan; Li, Yuan; Yang, Yongkang; Lee, Wayne Yuk Wai; Currie, Peter D; Lin, Changshuang; Jiang, Yanfu; Chen, Juyu; Tortorella, Micky D; Li, Hongyi; Li, Gang
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2023
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4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides

4-芳基吡咯烷类化合物作为一类新型口服有效抗疟药。第一部分：4-芳基-N-苄基吡咯烷-3-甲酰胺的评价

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.8b01972
Meyers, Marvin J; Liu, Jianguang; Xu, Jing; Leng, Fang; Guan, Jiantong; Liu, Zhijun; McNitt, Sarah A; Qin, Limei; Dai, Linglin; Ma, Hongwei; Adah, Dickson; Zhao, Siting; Li, Xiaofen; Polino, Alex J; Nasamu, Armiyaw S; Goldberg, Daniel E; Liu, Xiaorong; Lu, Yongzhi; Tu, Zhengchao; Chen, Xiaoping; Tortorella, Micky D
发表日期：2019
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Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets

基因工程小鼠模型揭示蛋白酶作为骨关节炎药物靶点的重要性

期刊:Current Rheumatology Reports
影响因子:3.9
doi:10.1007/s11926-013-0350-2
Miller, Rachel E; Lu, Yongzhi; Tortorella, Micky D; Malfait, Anne-Marie
关节炎
Mouse
发表日期：2013
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A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

PACE4在骨关节炎疼痛中的作用：来自人类遗传关联和无效突变表型的证据

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2011-200300
Malfait, Anne-Marie; Seymour, Albert B; Gao, Feng; Tortorella, Micky D; Le Graverand-Gastineau, Marie-Pierre Hellio; Wood, Linda S; Doherty, Michael; Doherty, Sally; Zhang, Weiya; Arden, Nigel K; Vaughn, Frances L; Leaverton, Paul E; Spector, Tim D; Hart, Deborah J; Maciewicz, Rose A; Muir, Kenneth R; Das, Rosalina; Sorge, Robert E; Sotocinal, Susanna G; Schorscher-Petcu, Ara; Valdes, Ana M; Mogil, Jeffrey S
关节炎
发表日期：2012
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Transport and equilibrium uptake of a peptide inhibitor of PACE4 into articular cartilage is dominated by electrostatic interactions

PACE4肽抑制剂向关节软骨的转运和平衡吸收主要受静电相互作用控制。

期刊:Archives of Biochemistry and Biophysics
影响因子:3
doi:10.1016/j.abb.2010.04.019
Byun, Sangwon; Tortorella, Micky D; Malfait, Anne-Marie; Fok, Kam; Frank, Eliot H; Grodzinsky, Alan J
发表日期：2010
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