日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deep-learning structure elucidation from single-mutant deep mutational scanning

基于单突变深度突变扫描的深度学习结构解析

Drake, Zachary C; Day, Elijah H; Toth, Paul D; Lindert, Steffen

Structural and Mechanistic Insights into Atypical Bacterial Topoisomerase Inhibitors

非典型细菌拓扑异构酶抑制剂的结构和机制研究

Toth, Paul D; Ratigan, Steven C; Powell, Joshua W; Cassel, Sydney R; Yalowich, Jack C; McElroy, Craig A; Lindert, Steffen; Bell, Charles E; Mitton-Fry, Mark J

EphA2 and Ephrin-A1 Utilize the Same Interface for Both in cis and in trans Interactions That Differentially Regulate Cell Signaling and Function.

EphA2 和 Ephrin-A1 利用相同的界面进行顺式和反式相互作用,从而差异性地调节细胞信号传导和功能

Kim Soyeon, Toth Paul, Wang Wei, Seiradake Elena, Shi Xiaojun, Wang Bingcheng

Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening

计算机筛选辅助开发新型细菌拓扑异构酶抑制剂

Powell, Joshua W; Mann, Chelsea A; Toth, Paul D; Nolan, Sheri; Steinert, Anja; Ove, Clarissa; Seffernick, Justin T; Wozniak, Daniel J; Kebriaei, Razieh; Lindert, Steffen; Osheroff, Neil; Yalowich, Jack C; Mitton-Fry, Mark J

Time-resolved live-cell spectroscopy reveals EphA2 multimeric assembly

时间分辨活细胞光谱揭示了EphA2多聚体的组装

Shi, Xiaojun; Lingerak, Ryan; Herting, Cameron J; Ge, Yifan; Kim, Soyeon; Toth, Paul; Wang, Wei; Brown, Benjamin P; Meiler, Jens; Sossey-Alaoui, Khalid; Buck, Matthias; Himanen, Juha; Hambardzumyan, Dolores; Nikolov, Dimitar B; Smith, Adam W; Wang, Bingcheng

Serotonin-1A receptor, a psychiatric disease risk factor, influences offspring immunity via sex-dependent genetic nurture

血清素-1A受体是精神疾病的风险因素,它通过性别依赖的遗传因素影响后代的免疫力。

Rosa J Chen ,Anika Nabila ,Swati Phalke ,Danny Flores Castro ,Judit Gal Toth ,Paul Bergin ,Jeroen Bastiaans ,Heidi Stuhlmann ,Alessandra B Pernis ,Miklos Toth

Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer's Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated

阿尔茨海默病脑病理学中位点特异性脑脊液 Tau 过度磷酸化:并非所有 Tau 磷酸化位点都过度磷酸化

Nicolas R Barthélemy, Balazs Toth, Paul T Manser, Sandra Sanabria-Bohórquez, Edmond Teng, Michael Keeley, Randall J Bateman, Robby M Weimer, Kristin R Wildsmith

CDKL5 kinase controls transcription-coupled responses to DNA damage

CDKL5激酶控制DNA损伤的转录偶联反应

Taran Khanam,Ivan Muñoz,Florian Weiland,Thomas Carroll,Michael Morgan,Barbara N Borsos,Vasiliki Pantazi,Meghan Slean,Miroslav Novak,Rachel Toth,Paul Appleton,Tibor Pankotai,Houjiang Zhou,John Rouse

RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health

RPA 介导的 E3 连接酶 RFWD3 募集对于链间交联修复和人类健康至关重要

Laura Feeney, Ivan M Muñoz, Christophe Lachaud, Rachel Toth, Paul L Appleton, Detlev Schindler, John Rouse