日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores.

一种能够快速抑制 PP2A-B56 磷酸酶的化学遗传系统揭示了其在有丝分裂中期着丝粒中的作用

Allan Lindsey A, Corno Andrea, Valverde Juan Manuel, Toth Rachel, Ly Tony, Saurin Adrian T

Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling.

激酶组筛选发现整合应激反应激酶 EIF2AK1/HRI 是 PINK1 线粒体自噬信号的负调控因子

Singh Pawan K, Agarwal Shalini, Volpi Ilaria, Wilhelm Léa P, Becchi Giada, Keenlyside Andrew, Macartney Thomas, Toth Rachel, Rousseau Adrien, Masson Glenn R, Ganley Ian G, Muqit Miratul M K

A fluorescence lifetime-based FLIM-timer for measuring the protein turnover of transcription factor Nrf2 in live cells.

一种基于荧光寿命的 FLIM 计时器,用于测量活细胞中转录因子 Nrf2 的蛋白质周转率

Dikovskaya Dina, Bento-Pereira Claudia, Shiga Kanade, Corno Andrea, Higgins Maureen, Toth Rachel, Saurin Adrian T, Dinkova-Kostova Albena T

Phosphorylation enables progressive microtubule-associated protein proteolysis and functionalisation during neural development.

磷酸化作用能够促进神经发育过程中微管相关蛋白的逐步水解和功能化。

Yang Zedeng, Liczmanska Magda, Hogg Elizabeth K J, Wallace Iona, Zhou Houjiang, Gourlay Robert, Squires Iolo, Li Ziyi, Hao Ying, Brown Fiona, Toth Rachel, Macartney Thomas, Hastie C James, Qi Yu Andy, Gierlinski Marek, Bustos Francisco, Findlay Greg M

Publisher's Note: ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase

编者按:ZNRF2 由生长因子从细胞膜释放,并与 ZNRF1 共同调节 Na+/K+ATPase。

Hoxhaj, Gerta; Najafov, Ayaz; Toth, Rachel; Campbell, David G; Prescott, Alan R; MacKintosh, Carol

Activity-based probe profiling of RNF12 E3 ubiquitin ligase function in Tonne-Kalscheuer syndrome

基于活性的探针分析 RNF12 E3 泛素连接酶在 Tonne-Kalscheuer 综合征中的功能

Bustos, Francisco; Mathur, Sunil; Espejo-Serrano, Carmen; Toth, Rachel; Hastie, C James; Virdee, Satpal; Findlay, Greg M

An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells

ERK5-KLF2信号模块调控早期胚胎基因表达和干细胞端粒再生

Brown, Helen A; Williams, Charles A C; Zhou, Houjiang; Rios-Szwed, Diana; Fernandez-Alonso, Rosalia; Mansoor, Saria; McMulkin, Liam; Toth, Rachel; Gourlay, Robert; Peltier, Julien; Dieguez-Martinez, Nora; Trost, Matthias; Lizcano, Jose M; Stavridis, Marios P; Findlay, Greg M

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity

Parkin-磷酸泛素复合物揭示了RBR连接酶活性所需的隐蔽泛素结合位点

Kumar, Atul; Chaugule, Viduth K; Condos, Tara E C; Barber, Kathryn R; Johnson, Clare; Toth, Rachel; Sundaramoorthy, Ramasubramanian; Knebel, Axel; Shaw, Gary S; Walden, Helen

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia

奇特的盟友:核因子Erf2和缺氧诱导因子1 (HIF-1)在肿瘤缺氧中的作用

Toth, Rachel K; Warfel, Noel A

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages.

分化过程中抑制 SIK2 和 SIK3 可增强巨噬细胞的抗炎表型

Darling Nicola J, Toth Rachel, Arthur J Simon C, Clark Kristopher