日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial DNA Instability Supersedes Parkin Mutations in Driving Mitochondrial Proteomic Alterations and Functional Deficits in Polg Mutator Mice

在Polg突变小鼠中,线粒体DNA不稳定性比Parkin突变更能驱动线粒体蛋白质组改变和功能缺陷。

Trease, Andrew J; Totusek, Steven; Lichter, Eliezer Z; Stauch, Kelly L; Fox, Howard S

Dysregulated cholesterol metabolism, aberrant excitability and altered cell cycle of astrocytes in fragile X syndrome

脆性X综合征中星形胶质细胞的胆固醇代谢紊乱、异常兴奋性和细胞周期改变

Baiyan Ren ,Maria Burkovetskaya ,Yoosun Jung ,Lara Bergdolt ,Steven Totusek ,Veronica Martinez-Cerdeno ,Kelly Stauch ,Zeljka Korade ,Anna Dunaevsky

Longitudinal in vivo metabolic labeling reveals tissue-specific mitochondrial proteome turnover rates and proteins selectively altered by parkin deficiency

纵向体内代谢标记揭示了组织特异性线粒体蛋白质组的周转率和帕金缺乏症选择性改变的蛋白质

K L Stauch #, S Totusek #, A J Trease #, L D Estrella, K Emanuel, A Fangmeier, H S Fox

Parkinson's disease relevant pathological features are manifested in male Pink1/Parkin deficient rats

雄性 Pink1/Parkin 缺陷大鼠表现出帕金森病相关病理特征

Benjamin G Lamberty, L Daniel Estrella, Jane E Mattingly, Katy Emanuel, Andrew Trease, Steven Totusek, Lexi Sheldon, Joseph W George, Mohannad A Almikhlafi, Trey Farmer, Kelly L Stauch

Hyperphosphorylated Human Tau Accumulates at the Synapse, Localizing on Synaptic Mitochondrial Outer Membranes and Disrupting Respiration in a Mouse Model of Tauopathy

过度磷酸化的人类 Tau 蛋白在突触处聚集,定位于突触线粒体外膜上,并扰乱 Tau 蛋白病小鼠模型中的呼吸

Andrew J Trease, Joseph W George, Nashanthea J Roland, Eliezer Z Lichter, Katy Emanuel, Steven Totusek, Howard S Fox, Kelly L Stauch

Neurocognitive status and risk of mortality among people living with human immunodeficiency virus: an 18-year retrospective cohort study

人类免疫缺陷病毒感染者的神经认知状态与死亡风险:一项为期18年的回顾性队列研究

Naveed, Zaeema; Fox, Howard S; Wichman, Christopher S; Alam, Morshed; May, Pamela; Arcari, Christine M; Meza, Jane; Totusek, Steven; Baccaglini, Lorena

Applying the RatWalker System for Gait Analysis in a Genetic Rat Model of Parkinson's Disease

将RatWalker系统应用于帕金森病遗传大鼠模型的步态分析

Stauch, Kelly L; Totusek, Steven; Farmer, Trey; Lamberty, Benjamin G; Dyball, Kelsey N; Almikhlafi, Mohannad A; Fox, Howard S

Quantitative Proteomics of Presynaptic Mitochondria Reveal an Overexpression and Biological Relevance of Neuronal MitoNEET in Postnatal Brain Development

突触前线粒体的定量蛋白质组学揭示了神经元 MitoNEET 在出生后大脑发育中的过度表达和生物学相关性

Kelly L Stauch, Lance M Villeneuve, Steven Totusek, Benjamin Lamberty, Pawel Ciborowski, Howard S Fox