Towlerton相关文献与解析，生知库 | 链接生命科学的每一步

Herpesviruses Reactivation and Systemic Inflammation Before and After Initiating Antiretroviral Therapy Among Women with HIV in Rakai, Uganda

乌干达拉凯地区感染艾滋病毒的女性在开始抗逆转录病毒治疗前后疱疹病毒再激活和全身炎症情况

Ssempijja, Victor; Callier, Viviane; Nason, Martha; Anok, Aggrey; Lisco, Andrea; Redd, Andrew D; Quinn, Thomas C; Rupert, Adam; Towlerton, Andrea; Das, Sanchita; Walker, Lorenzo; Tomusange, Stephen; Kityamuweesi, Taddeo; Bbuule, Paul; Sereti, Irini; Reynolds, Steven J

炎症

HIV

炎症/感染

Immunology/Inflammation

T-cells specific for KSHV and HIV migrate to Kaposi sarcoma tumors and persist over time

针对KSHV和HIV的特异性T细胞会迁移至卡波西肉瘤肿瘤并长期存在。

期刊:

影响因子:

doi:10.1101/2024.02.06.579223

Ravishankar, Shashidhar; Towlerton, Andrea M H; Tiamiyu, Iyabode L; Mooka, Peter; Nankoma, Janet; Kafeero, James; Mubiru, Dennis; Sekitene, Semei; Aicher, Lauri D; Miller, Chris P; Coffey, David G; Okoche, Lazarus; Atwinirembabazi, Prisca; Okonye, Joseph; White, Jessica; Koelle, David M; Jing, Lichen; Phipps, Warren T; Warren, Edus H

Class II HLA-DRB4 is a predictive biomarker for survival following immunotherapy in metastatic non-small cell lung cancer

II类HLA-DRB4是转移性非小细胞肺癌免疫治疗后生存的预测性生物标志物。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-023-48546-y

Jiang, Cindy Y; Zhao, Lili; Green, Michael D; Ravishankar, Shashidhar; Towlerton, Andrea M H; Scott, Anthony J; Raghavan, Malini; Cusick, Matthew F; Warren, Edus H; Ramnath, Nithya

Serial Analysis of the T-Cell Receptor β-Chain Repertoire in People Living With HIV Reveals Incomplete Recovery After Long-Term Antiretroviral Therapy

对艾滋病毒感染者T细胞受体β链库的系列分析显示，长期抗逆转录病毒治疗后恢复不完全

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2022.879190

Towlerton, Andrea M H; Ravishankar, Shashidhar; Coffey, David G; Puronen, Camille E; Warren, Edus H

Genomic changes in Kaposi Sarcoma-associated Herpesvirus and their clinical correlates

卡波西肉瘤相关疱疹病毒的基因组变化及其临床相关性

期刊:PLoS Pathogens

影响因子:5.5

doi:10.1371/journal.ppat.1010524

Jan Clement Santiago, Scott V Adams, Andrea Towlerton, Fred Okuku, Warren Phipps, James I Mullins

Integrated TCR repertoire analysis and single-cell transcriptomic profiling of tumor-infiltrating T cells in renal cell carcinoma identifies shared and tumor-restricted expanded clones with unique phenotypes

肾细胞癌中肿瘤浸润 T 细胞的综合 TCR 库分析和单细胞转录组分析可识别具有独特表型的共享和肿瘤限制性扩增克隆

期刊:Frontiers in Oncology

影响因子:3.5

doi:10.3389/fonc.2022.952252

Yuexin Xu, Alicia J Morales, Andrea M H Towlerton, Shreeram Akilesh, Chris P Miller, Scott S Tykodi, Edus H Warren

Ultradeep, targeted sequencing reveals distinct mutations in blood compared to matched bone marrow among patients with multiple myeloma

超深度靶向测序揭示了多发性骨髓瘤患者血液中与匹配骨髓中不同的突变

期刊:Blood Cancer Journal

影响因子:11.6

doi:10.1038/s41408-019-0238-0

Coffey, David G; Wu, Qian V; Towlerton, Andrea M H; Ornelas, Sharon; Morales, Alicia J; Xu, Yuexin; Green, Damian J; Warren, Edus H

Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma

针对肾细胞癌 5T4 肿瘤抗原的 T 细胞受体工程化 T 细胞疗法的临床前开发

期刊:Cancer Immunology Immunotherapy

影响因子:8.1

doi:10.1007/s00262-019-02419-4

Yuexin Xu, Alicia J Morales, Michael J Cargill, Andrea M H Towlerton, David G Coffey, Edus H Warren, Scott S Tykodi

Capacity building for hematologic malignancies in Uganda: a comprehensive research, training, and care program through the Uganda Cancer Institute-Fred Hutchinson Cancer Research Center collaboration

乌干达血液系统恶性肿瘤能力建设：通过乌干达癌症研究所-弗雷德·哈钦森癌症研究中心合作开展的综合性研究、培训和护理项目

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2018GS111079

Okello, Clement D; Ddungu, Henry; Omoding, Abrahams; Towlerton, Andrea M H; Pitorak, Heather; Maggard, Katie; Ewart, Sarah; Phipps, Warren T; Uldrick, Thomas S; Warren, Edus H; Orem, Jackson

Exome Sequencing Reveals a Sparse Genomic Landscape in Kaposi Sarcoma.

外显子组测序揭示卡波西肉瘤基因组图谱稀疏

Herpesviruses Reactivation and Systemic Inflammation Before and After Initiating Antiretroviral Therapy Among Women with HIV in Rakai, Uganda

乌干达拉凯地区感染艾滋病毒的女性在开始抗逆转录病毒治疗前后疱疹病毒再激活和全身炎症情况

T-cells specific for KSHV and HIV migrate to Kaposi sarcoma tumors and persist over time

针对KSHV和HIV的特异性T细胞会迁移至卡波西肉瘤肿瘤并长期存在。

Class II HLA-DRB4 is a predictive biomarker for survival following immunotherapy in metastatic non-small cell lung cancer

II类HLA-DRB4是转移性非小细胞肺癌免疫治疗后生存的预测性生物标志物。

Serial Analysis of the T-Cell Receptor β-Chain Repertoire in People Living With HIV Reveals Incomplete Recovery After Long-Term Antiretroviral Therapy

对艾滋病毒感染者T细胞受体β链库的系列分析显示，长期抗逆转录病毒治疗后恢复不完全

Genomic changes in Kaposi Sarcoma-associated Herpesvirus and their clinical correlates

卡波西肉瘤相关疱疹病毒的基因组变化及其临床相关性

Integrated TCR repertoire analysis and single-cell transcriptomic profiling of tumor-infiltrating T cells in renal cell carcinoma identifies shared and tumor-restricted expanded clones with unique phenotypes

肾细胞癌中肿瘤浸润 T 细胞的综合 TCR 库分析和单细胞转录组分析可识别具有独特表型的共享和肿瘤限制性扩增克隆

Ultradeep, targeted sequencing reveals distinct mutations in blood compared to matched bone marrow among patients with multiple myeloma

超深度靶向测序揭示了多发性骨髓瘤患者血液中与匹配骨髓中不同的突变

Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma

针对肾细胞癌 5T4 肿瘤抗原的 T 细胞受体工程化 T 细胞疗法的临床前开发

Capacity building for hematologic malignancies in Uganda: a comprehensive research, training, and care program through the Uganda Cancer Institute-Fred Hutchinson Cancer Research Center collaboration

乌干达血液系统恶性肿瘤能力建设：通过乌干达癌症研究所-弗雷德·哈钦森癌症研究中心合作开展的综合性研究、培训和护理项目