日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cereblon induces G3BP2 neosubstrate degradation using molecular surface mimicry

Cereblon利用分子表面模拟诱导G3BP2新底物降解

Annunziato, Stefano; Quan, Chao; Donckele, Etienne J; Lamberto, Ilaria; Bunker, Richard D; Zlotosch, Mary; Schwander, Laura; Murthy, Anastasia; Wiedmer, Lars; Staehly, Camille; Matysik, Michelle; Gilberto, Samuel; Kapsitidou, Despina; Wible, Daric; De Donatis, Gian Marco; Trenh, Peter; SriRamaratnam, Rohitha; Strande, Vaik; Lieberherr, Raphael; Lyon, David; Steiner, Danielle; Silva, Joao; Almeida, Reinaldo; Dolgikh, Elena; DeMarco, Bradley; Tsai, Jennifer; Sadok, Amine; Zarayskiy, Vladislav; Walter, Magnus; Tiedt, Ralph; Lumb, Kevin J; Bonenfant, Debora; Fasching, Bernhard; Castle, John C; Townson, Sharon A; Gainza, Pablo; Petzold, Georg

A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.

类似降解子的分子胶驱动 CRBN 同源二聚化和降解。

Langousis Gerasimos, Gainza Pablo, Hunkeler Moritz, Kapsitidou Despoina, Donckele Etienne J, Annunziato Stefano, Wiedmer Lars, Jones Katherine F M, DeMarco Bradley, Quan Chao, Bunker Richard D, Lumb Kevin J, Fasching Bernhard, Castle John C, Townson Sharon A, Bonenfant Débora

NMR (1)H,(13)C, (15)N backbone and (13)C side chain resonance assignment of the G12C mutant of human K-Ras bound to GDP

人K-Ras G12C突变体与GDP结合的NMR (1)H、(13)C、(15)N主链和(13)C侧链共振归属

Sharma, Alok K; Lee, Seung-Joo; Rigby, Alan C; Townson, Sharon A

Design of a superior cytokine antagonist for topical ophthalmic use.

设计一种适用于眼科局部用药的优良细胞因子拮抗剂

Hou Jinzhao, Townson Sharon A, Kovalchin Joseph T, Masci Allyson, Kiner Olga, Shu Yanqun, King Bracken M, Schirmer Emily, Golden Kathryn, Thomas Christoph, Garcia K Christopher, Zarbis-Papastoitsis Gregory, Furfine Eric S, Barnes Thomas M

Crystallization and preliminary crystallographic analysis of the type IIL restriction enzyme MmeI in complex with DNA

MmeI 与 DNA 复合物的结晶及初步晶体学分析(MmeI 为 IIL 型限制性内切酶)

Callahan, Scott J; Morgan, Richard D; Jain, Rinku; Townson, Sharon A; Wilson, Geoffrey G; Roberts, Richard J; Aggarwal, Aneel K