日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lung cancer-enriched p53 mutants occupy canonical p53 target genes without activating transcription, revealing a distinct loss-of-function behavior.

肺癌富集的 p53 突变体占据了典型的 p53 靶基因,但并未激活转录,表现出明显的失功能行为。

Tracewell Mason A, Shankle Hailey N, Barnada Samantha M, Vyas Khushali S, Kim Kevin M, Qyshkollari Theodhora, Karlin Jonathan E, Barta Julie A, McMahon Steven B

Genomic features underlie the co-option of SVA transposons as cis-regulatory elements in human pluripotent stem cells

基因组特征决定了 SVA 转座子在人类多能干细胞中作为顺式调控元件的作用

Samantha M Barnada, Andrew Isopi, Daniela Tejada-Martinez, Clément Goubert, Sruti Patoori, Luca Pagliaroli, Mason Tracewell, Marco Trizzino

The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22

SAGA复合物通过其去泛素化酶模块亚基USP22调控转录的早期步骤。

Timothy J Stanek ,Victoria J Gennaro ,Mason A Tracewell ,Daniela Di Marcantonio ,Kristen L Pauley ,Sabrina Butt ,Christopher McNair ,Feng Wang ,Andrew V Kossenkov ,Karen E Knudsen ,Tauseef Butt ,Stephen M Sykes ,Steven B McMahon

Conventional and Organic Wheat Germ Have Distinct Physiological Effects in the Tobacco Hornworm, Manduca Sexta: Use of Black Mutant Assay to Detect Environmental Juvenoid Activity of Insect Growth Regulators

常规小麦胚芽和有机小麦胚芽对烟草天蛾(Manduca sexta)具有不同的生理效应:利用黑突变体试验检测昆虫生长调节剂的环境保幼激素活性

Ffrench, Jivonsha; Tracewell, Jaime; Suzuki, Yuichiro

Evobrutinib, a covalent Bruton's tyrosine kinase inhibitor: Mass balance, elimination route, and metabolism in healthy participants

Evobrutinib,一种共价布鲁顿酪氨酸激酶抑制剂:健康受试者体内的质量平衡、消除途径和代谢

Scheible, Holger; Dyroff, Martin; Seithel-Keuth, Annick; Harrison-Moench, Eleanor; Mammasse, Nadra; Port, Andreas; Bachmann, Angelika; Dong, Jennifer; van Lier, Jan Jaap; Tracewell, William; Mitchell, David

Pharmacokinetic study and evaluation of the safety of taurolidine for dogs with osteosarcoma

牛磺罗定治疗犬骨肉瘤的药代动力学研究及安全性评价

Marley, Kevin; Helfand, Stuart C; Simpson, Jennifer; Mata, John E; Tracewell, William G; Brownlee, Lisa; Bracha, Shay; Séguin, Bernard

Directed enzyme evolution: climbing fitness peaks one amino acid at a time

定向酶进化:逐个氨基酸地攀登适应性高峰

Tracewell, Cara A; Arnold, Frances H

Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B(1) pharmacokinetics in human volunteers

叶绿素和叶绿素铜钠盐对人体志愿者低剂量黄曲霉毒素B1药代动力学的影响

Jubert, Carole; Mata, John; Bench, Graham; Dashwood, Roderick; Pereira, Cliff; Tracewell, William; Turteltaub, Kenneth; Williams, David; Bailey, George