日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model

FGFR3信号通路失调会改变膀胱癌的免疫微环境,并在基于代理的模型中展现出治疗潜力。

Bergman, Daniel R; Wang, Yixuan; Trujillo, Erica; Fernald, Anthony A; Li, Lie; Pearson, Alexander T; Sweis, Randy F; Jackson, Trachette L

Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy

基于代理的虚拟肿瘤建模揭示了微环境复杂性对免疫疗法疗效的关键影响

Wang, Yixuan; Bergman, Daniel R; Trujillo, Erica; Fernald, Anthony A; Li, Lie; Pearson, Alexander T; Sweis, Randy F; Jackson, Trachette L

Mathematical modeling insights into improving CAR T cell therapy for solid tumors with bystander effects

利用数学建模深入了解旁观者效应对实体瘤CAR-T细胞疗法的改进作用。

Kara, Erdi; Jackson, Trachette L; Jones, Chartese; Sison, Rockford; McGee Ii, Reginald L

Mathematical model predicts tumor control patterns induced by fast and slow cytotoxic T lymphocyte killing mechanisms

数学模型预测了由快速和慢速细胞毒性T淋巴细胞杀伤机制引起的肿瘤控制模式

Wang, Yixuan; Bergman, Daniel R; Trujillo, Erica; Pearson, Alexander T; Sweis, Randy F; Jackson, Trachette L

Phenotype switching in a global method for agent-based models of biological tissue

生物组织基于代理模型的全局方法中的表型转换

Bergman, Daniel; Jackson, Trachette L

Implementing a global approach for efficiently simulating molecular dynamics in agent-based models of biological tissue

实施一种全局方法,以高效地模拟生物组织基于代理模型中的分子动力学

Bergman, Daniel; Jackson, Trachette L

Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution

利用动态胃肠液对口服吸收模型进行机制解卷积,以预测胃肠道药物溶解的区域速率和程度

Yu, Alex; Koenigsknecht, Mark J; Hens, Bart; Baker, Jason R; Wen, Bo; Jackson, Trachette L; Pai, Manjunath P; Hasler, William; Amidon, Gordon L; Sun, Duxin

A mathematical model for IL-6-mediated, stem cell driven tumor growth and targeted treatment

IL-6介导的干细胞驱动肿瘤生长和靶向治疗的数学模型

Nazari, Fereshteh; Pearson, Alexander T; Nör, Jacques Eduardo; Jackson, Trachette L

A phase II trial of the BCL-2 homolog domain 3 mimetic AT-101 in combination with docetaxel for recurrent, locally advanced, or metastatic head and neck cancer

一项 II 期临床试验评估了 BCL-2 同源结构域 3 模拟物 AT-101 联合多西他赛治疗复发性、局部晚期或转移性头颈癌的疗效。

Swiecicki, Paul L; Bellile, Emily; Sacco, Assuntina G; Pearson, Alexander T; Taylor, Jeremy M G; Jackson, Trachette L; Chepeha, Douglas B; Spector, Matthew E; Shuman, Andrew; Malloy, Kelly; Moyer, Jeffrey; McKean, Erin; McLean, Scott; Sukari, Ammar; Wolf, Gregory T; Eisbruch, Avraham; Prince, Mark; Bradford, Carol; Carey, Thomas E; Wang, Shaomeng; Nör, Jacques E; Worden, Francis P

Patient-derived xenograft (PDX) tumors increase growth rate with time

患者来源的异种移植(PDX)肿瘤的生长速度随时间推移而加快

Pearson, Alexander T; Finkel, Kelsey A; Warner, Kristy A; Nör, Felipe; Tice, David; Martins, Manoela D; Jackson, Trachette L; Nör, Jacques E