日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FK506-Binding Protein like (FKBPL) Has an Important Role in Heart Failure with Preserved Ejection Fraction Pathogenesis with Potential Diagnostic Utility

FK506 结合蛋白样 (FKBPL) 在射血分数保留的心力衰竭发病机制中发挥重要作用,并具有潜在的诊断效用

Michael Chhor, Hao Chen, Djurdja Jerotić, Milorad Tešić, Valentina N Nikolić, Milan Pavlović, Rada M Vučić, Benjamin Rayner, Chris J Watson, Mark Ledwidge, Kenneth McDonald, Tracy Robson, Kristine C McGrath, Lana McClements

Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype

利用靶位阻断剂增强精氨酸酶2表达作为调节巨噬细胞表型的策略

Chiara De Santi ,Frances K Nally ,Remsha Afzal ,Conor P Duffy ,Stephen Fitzsimons ,Stephanie L Annett ,Tracy Robson ,Jennifer K Dowling ,Sally-Ann Cryan ,Claire E McCoy

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

线粒体精氨酸酶-2对于IL-10介导的炎症巨噬细胞代谢重编程至关重要。

Jennifer K Dowling # ,Remsha Afzal # ,Linden J Gearing ,Mariana P Cervantes-Silva ,Stephanie Annett ,Gavin M Davis ,Chiara De Santi ,Nadine Assmann ,Katja Dettmer ,Daniel J Gough ,Glenn R Bantug ,Fidinny I Hamid ,Frances K Nally ,Conor P Duffy ,Aoife L Gorman ,Alex M Liddicoat ,Ed C Lavelle ,Christoph Hess ,Peter J Oefner ,David K Finlay ,Gavin P Davey ,Tracy Robson ,Annie M Curtis ,Paul J Hertzog ,Bryan R G Williams ,Claire E McCoy

FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function

妊娠期糖尿病导致 FKBPL 和 SIRT-1 下调,影响血管生成和内皮功能

Abdelrahim Alqudah, Kelly-Ann Eastwood, Djurdja Jerotic, Naomi Todd, Denise Hoch, Ross McNally, Danilo Obradovic, Stefan Dugalic, Alyson J Hunter, Valerie A Holmes, David R McCance, Ian S Young, Chris J Watson, Tracy Robson, Gernot Desoye, David J Grieve, Lana McClements

Delivery of RALA/siFKBPL nanoparticles via electrospun bilayer nanofibres: An innovative angiogenic therapy for wound repair

通过电纺双层纳米纤维输送 RALA/siFKBPL 纳米粒子:一种用于伤口修复的创新血管生成疗法

Eoghan J Mulholland, Ahlam Ali, Tracy Robson, Nicholas J Dunne, Helen O McCarthy

FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4

FKBPL 及其肽衍生物通过下调 DLL4 和 Notch4 抑制内分泌治疗耐药性癌症干细胞和乳腺癌转移

Lana McClements, Stephanie Annett, Anita Yakkundi, Martin O'Rourke, Andrea Valentine, Nermeen Moustafa, Abdelrahim Alqudah, Bruno M Simões, Fiona Furlong, Amy Short, Stuart A McIntosh, Helen O McCarthy, Robert B Clarke, Tracy Robson

Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer

使用 RALA/iNOS 复合纳米粒子进行基因治疗可显著提高转移性前列腺癌模型的生存率

Cian M McCrudden, John W McBride, Joanne McCaffrey, Emma M McErlean, Nicholas J Dunne, Vicky L Kett, Jonathan A Coulter, Tracy Robson, Helen O McCarthy

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy

PTEN 缺陷促进巨噬细胞浸润和前列腺癌对 IAP 拮抗剂/放射联合治疗的高敏感性

Chris W D Armstrong, Pamela J Maxwell, Chee Wee Ong, Kelly M Redmond, Christopher McCann, Jessica Neisen, George A Ward, Gianni Chessari, Christopher Johnson, Nyree T Crawford, Melissa J LaBonte, Kevin M Prise, Tracy Robson, Manuel Salto-Tellez, Daniel B Longley, David J J Waugh

FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis

FKBPL 是发育和病理性血管生成的关键抗血管生成调节剂

Anita Yakkundi, Rachel Bennett, Ivette Hernández-Negrete, Jean-Marie Delalande, Mary Hanna, Oksana Lyubomska, Kenneth Arthur, Amy Short, Hayley McKeen, Laura Nelson, Cian M McCrudden, Ross McNally, Lana McClements, Helen O McCarthy, Alan J Burns, Roy Bicknell, Adrien Kissenpfennig, Tracy Robson

RALA-mediated delivery of FKBPL nucleic acid therapeutics

RALA 介导的 FKBPL 核酸疗法递送

Rachel Bennett, Anita Yakkundi, Hayley D McKeen, Lana McClements, Thomas J McKeogh, Cian M McCrudden, Kenneth Arthur, Tracy Robson, Helen O McCarthy