日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of a First-in-Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

发现一种具有免疫治疗活性的首创共价变构SHP1抑制剂

Qu, Zihan; Meke, Frederick Nguele; Zhang, Zheng; Krabill, Aaron D; Muli, Christine S; Jassim, Brenson A; Dong, Jiajun; Nguyen, Quyen D; Bai, Yunpeng; Li, Jinyue; Miao, Yiming; Asadi, Bardia; Johnson, Levi M; Miao, Jinmin; Trader, Darci J; Tao, W Andy; Zhang, Zhong-Yin

NMR-Guided Studies to Establish the Binding Interaction between a Peptoid and Protein

利用核磁共振引导的研究确定肽类化合物与蛋白质之间的结合相互作用

Muli, Christine S; Xie, Dan; Post, Carol Beth; Trader, Darci J

Activation of the 20S proteasome core particle prevents cell death induced by oxygen- and glucose deprivation in cultured cortical neurons.

20S蛋白酶体核心颗粒的激活可防止培养的皮层神经元因缺氧和缺糖而导致的细胞死亡

Salazar Ivan L, Curcio Michele, Mele Miranda, Vetrone Rossela, Frisari Simone, Costa Rui O, Caldeira Margarida V, Trader Darci J, Duarte Carlos B

Exploration of degrons and their ability to mediate targeted protein degradation

探索降解子及其介导靶向蛋白质降解的能力

Harris, Timothy J Jr; Trader, Darci J

Exploring the immunoproteasome's substrate preferences for improved hydrolysis and selectivity

探索免疫蛋白酶体的底物偏好以提高水解和选择性

Muli, Christine S; Loy, Cody A; Trader, Darci J

Primed for Interactions: Investigating the Primed Substrate Channel of the Proteasome for Improved Molecular Engagement

为相互作用做好准备:研究蛋白酶体的底物激活通道以改善分子结合

Loy, Cody A; Trader, Darci J

Caged aminoluciferin probe for bioluminescent immunoproteasome activity analysis

用于生物发光免疫蛋白酶体活性分析的笼状氨基荧光素探针

Loy, Cody A; Trader, Darci J

Discovery and Development of Cyclic Peptide Proteasome Stimulators

环肽蛋白酶体刺激剂的发现与开发

Nelson, Samantha; Harris, Timothy J; Muli, Christine S; Maresh, Marianne E; Baker, Braden; Smith, Chloe; Neumann, Chris; Trader, Darci J; Parkinson, Elizabeth I

Synthesis and Application of a Versatile Immunoproteasome Activity Probe

一种多功能免疫蛋白酶体活性探针的合成与应用

Halder, Saayak; Loy, Cody A; Trader, Darci J

Synthesis and Application of a Caged Bioluminescent Probe for the Immunoproteasome.

合成及应用笼状生物发光探针检测免疫蛋白酶体

Loy Cody A, Trader Darci J