日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Erratum to "INTERCEPT-AD, a phase 1 study of intravenous sabirnetug in participants with mild cognitive impairment or mild dementia due to Alzheimer's disease" [J Prev Alzheimers Dis 2025;12(1): 100005.]

更正“INTERCEPT-AD,一项针对患有轻度认知障碍或轻度痴呆(由阿尔茨海默病引起)的参与者的静脉注射沙比奈妥的 1 期研究”[J Prev Alzheimers Dis 2025;12(1): 100005.]

Siemers, Eric; Feaster, Todd; Sethuraman, Gopalan; Sundell, Karen; Skljarevski, Vladimir; Cline, Erika N; Zhang, Hao; Jerecic, Jasna; Honig, Lawrence S; Salloway, Stephen; Sperling, Reisa; Trame, Mirjam N; Dodds, Michael G; Johnson, Kimball

INTERCEPT-AD, a phase 1 study of intravenous sabirnetug in participants with mild cognitive impairment or mild dementia due to Alzheimer's disease

INTERCEPT-AD 是一项针对患有轻度认知障碍或由阿尔茨海默病引起的轻度痴呆的患者的静脉注射沙比妥类药物的 1 期研究。

Siemers, Eric; Feaster, Todd; Sethuraman, Gopalan; Sundell, Karen; Skljarevski, Vladimir; Cline, Erika N; Zhang, Hao; Jerecic, Jasna; Honig, Lawrence S; Salloway, Stephen; Sperling, Reisa; Trame, Mirjam N; Dodds, Michael G; Johnson, Kimball

Compounding heterochrony shapes the salamander visual system across adaptive zones

复合异时性塑造了蝾螈在适应区内的视觉系统

Bonett, Ronald M; Bierbaum, Emily L; Hess, Alexander J; Trame, Samantha D; Eckhardt, Campbell W; Herrboldt, Madison A; McGouran, Carissa N; Kolozsvary, Andrew D; Sowell, Sydney; Flusche, Ann Marie; McGlone, Rhiannon

Covariate modeling in pharmacometrics: General points for consideration

药物计量学中的协变量建模:需要考虑的一般要点

Sanghavi, Kinjal; Ribbing, Jakob; Rogers, James A; Ahmed, Mariam A; Karlsson, Mats O; Holford, Nick; Chasseloup, Estelle; Ahamadi, Malidi; Kowalski, Kenneth G; Cole, Susan; Kerwash, Essam; Wade, Janet R; Liu, Chao; Wang, Yaning; Trame, Mirjam N; Zhu, Hao; Wilkins, Justin J

A case study of a patient-centered reverse translational systems-based approach to understand adverse event profiles in drug development

以患者为中心,运用反向转化系统方法研究药物研发中不良事件特征

Kim, Sarah; Lahu, Gezim; Vakilynejad, Majid; Soldatos, Theodoros G; Jackson, David B; Lesko, Lawrence J; Trame, Mirjam N

Quality of life, distress, and posttraumatic growth 5 years after colorectal cancer diagnosis according to history of inpatient rehabilitation

根据住院康复史,结直肠癌诊断五年后患者的生活质量、痛苦程度和创伤后成长情况

Scherer-Trame, Sophie; Jansen, Lina; Koch-Gallenkamp, Lena; Arndt, Volker; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann

Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities

用于评估新分子实体临床前心血管安全性分析中心脏收缩力和血液动力学的半机制建模平台

Venkatasubramanian, Raja; Collins, Teresa A; Lesko, Lawrence J; Mettetal, Jerome T; Trame, Mirjam N

Quantitative Systems Pharmacology Model-Based Predictions of Clinical Endpoints to Optimize Warfarin and Rivaroxaban Anti-Thrombosis Therapy

基于定量系统药理学模型的临床终点预测,以优化华法林和利伐沙班抗血栓治疗

Hartmann, Sonja; Biliouris, Konstantinos; Lesko, Lawrence J; Nowak-Göttl, Ulrike; Trame, Mirjam N

Performance of the SAEM and FOCEI Algorithms in the Open-Source, Nonlinear Mixed Effect Modeling Tool nlmixr

SAEM 和 FOCEI 算法在开源非线性混合效应建模工具 nlmixr 中的性能

Schoemaker, Rik; Fidler, Matthew; Laveille, Christian; Wilkins, Justin J; Hooijmaijers, Richard; Post, Teun M; Trame, Mirjam N; Xiong, Yuan; Wang, Wenping

Perspective on the State of Pharmacometrics and Systems Pharmacology Integration

药物计量学与系统药理学整合现状展望

Trame, Mirjam N; Riggs, Matthew; Biliouris, Konstantinos; Marathe, Dhananjay; Mettetal, Jerome; Post, Teun M; Rizk, Matthew L; Visser, Sandra A G; Musante, Cynthia J