Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma.
同时抑制从头合成谷胱甘肽和核苷酸生物合成对胶质母细胞瘤具有合成致死性
期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.115596
Udutha Suresh, Taglang Céline, Batsios Georgios, Gillespie Anne Marie, Tran Meryssa, Hoeve Johanna Ten, Graeber Thomas G, Viswanath Pavithra