A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration
对伴有和不伴有HIV相关痴呆的HIV感染者额叶皮层进行全基因组mRNA和microRNA平行分析,揭示了轴突导向及其下游通路在HIV介导的神经退行性变中的作用。
期刊:BMC Genomics
影响因子:3.7
doi:10.1186/1471-2164-13-677
Zhou, Li; Pupo, Gulietta M; Gupta, Priyanka; Liu, Bing; Tran, Sieu L; Rahme, Raany; Wang, Bin; Rua, Rejane; Rizos, Helen; Carroll, Adam; Cairns, Murray J; Saksena, Nitin K