Reverse-phase chromatography removes double-stranded RNA, fragments, and residual template to decrease immunogenicity and increase cell potency of mRNA and saRNA.
反相色谱法可去除双链 RNA、片段和残留模板，从而降低 mRNA 和 saRNA 的免疫原性并提高其细胞效力
期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102491
KruÅ¡iÄ Andreja, Mencin Nina, Leban Marta, Nett Evelin, PerkoviÄ Mario, Sahin Ugur, MeguÅ¡ar Polona, Å trancar AleÅ¡, Sekirnik Rok
