日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2

CACHE挑战赛#3:靶向SARS-CoV-2的Nsp3宏结构域

Herasymenko, Oleksandra; Silva, Madhushika; Correy, Galen J; Abu-Saleh, Abd Al-Aziz A; Ackloo, Suzanne; Arrowsmith, Cheryl; Ashworth, Alan; Ban, Fuqiang; Beck, Hartmut; Bishop, Kevin P; Bohórquez, Hugo J; Bolotokova, Albina; Breznik, Marko; Chau, Irene; Chen, Yu; Cherkasov, Artem; Dehaen, Wim; Della Corte, Dennis; Denzinger, Katrin; Doering, Niklas P; Edfeldt, Kristina; Edwards, Aled; Fayne, Darren; Gentile, Francesco; Gibson, Elisa; Gokdemir, Ozan; Gunnarsson, Anders; Günther, Judith; Irwin, John J; Jensen, Jan Halborg; Harding, Rachel J; Hillisch, Alexander; Hoffer, Laurent; Hogner, Anders; Hutchinson, Ashley; Kandwal, Shubhangi; Karlova, Andrea; Koirala, Kushal; Kotelnikov, Sergei; Kozakov, Dima; Lee, Juyong; Lee, Soowon; Lessel, Uta; Liu, Sijie; Liu, Xuefeng; Loppnau, Peter; Meiler, Jens; Moretti, Rocco; Moroz, Yurii S; Muvva, Charuvaka; Oprea, Tudor I; Paige, Brooks; Pandit, Amit; Park, Keunwan; Poda, Gennady; Protopopov, Mykola V; Pütter, Vera; Ravichandran, Rahul; Rognan, Didier; Rosta, Edina; Sabnis, Yogesh; Scott, Thomas; Seitova, Almagul; Sharma, Purshotam; Sindt, François; Song, Minghu; Steinmann, Casper; Stevens, Rick; Talagayev, Valerij; Tararina, Valentyna V; Tarkhanova, Olga; Tingey, Damon; Trant, John F; Treleaven, Dakota; Tropsha, Alexander; Walters, Patrick; Wells, Jude; Westermaier, Yvonne; Wolber, Gerhard; Wortmann, Lars; Zheng, Shuangjia; Fraser, James S; Schapira, Matthieu

We Licked the Toads so You Don't Have to: A Comprehensive Analysis of the Chemical Syntheses of the Classical Psychedelics Bufotenin(e) and 5-Methoxy-N,N-Dimethyltryptamine

我们舔过蟾蜍,所以你不用再舔了:经典迷幻剂蟾毒色胺(e)和5-甲氧基-N,N-二甲基色胺化学合成的综合分析

Homon, Anton; Laramie, Jaxon; Hayward, John J; Trant, John F

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins.

利用高通量筛选方法发现潜在的结直肠癌化疗药物:重新利用药物来识别 14-3-3 蛋白的新型破坏剂。

He Siyi, Meister Daniel, Khan Samra, Mohammadzadeh Azam, Delgadillo Silva Luis, Rutter Guy A, Trant John F, Lim Gareth E

Correction: The biosynthesis of the cannabinoids

更正:大麻素的生物合成

Tahir, M Nazir; Raz, Farsheed Shahbazi; Rondeau-Gagné, Simon; Trant, John F

Synthesis and X‑ray Structures of Bis-Functional Resorcinarene Crown Ethers

双功能间苯二酚冠醚的合成及X射线结构

Osei, Frank Boateng; Nadimi, Sanaz; Ward, Jas S; Nasri, Sarah; Abu-Saleh, Abd Al-Aziz A; Pourian, Elham; Trant, John F; Rissanen, Kari; Beyeh, Ngong Kodiah

Boron in My Mind: A Comprehensive Review of the Evolution of the Diverse Syntheses of 4-Borono-l-Phenylalanine, the Leading Agent for Boron Neutron Capture Therapy

硼在我心中:4-硼酸-1-苯丙氨酸(硼中子俘获疗法的主要试剂)多种合成方法演变的全面综述

Ahmad, Sarfraz; Pan, Ming; Hayward, John J; Sementilli, Massimo; Porter, Lisa A; Trant, John F

Cancer cell extravasation requires (i)plectin-mediated delivery of MT1-MMP at invadopodia.

癌细胞外渗需要(i)plectin介导的MT1-MMP在侵袭伪足处的递送

Grafinger Olivia R, Hayward John J, Meng Ying, Geddes-McAlister Jennifer, Li Yan, Mar Sara, Sheng Minzhi, Su Boyang, Thillainadesan Gobi, Lipsman Nir, Coppolino Marc G, Trant John F, Jerzak Katarzyna J, Leong Hon S

Pharmacophore-Assisted Covalent Docking Identifies a Potential Covalent Inhibitor for Drug-Resistant Genotype 3 Variants of Hepatitis C Viral NS3/4A Serine Protease

药效团辅助共价对接鉴定出一种针对丙型肝炎病毒NS3/4A丝氨酸蛋白酶耐药基因型3变体的潜在共价抑制剂

Iman, Kanzal; Mirza, Muhammad Usman; Sadia, Fazila; Froeyen, Matheus; Trant, John F; Chaudhary, Safee Ullah

Water-mediated ribonucleotide-amino acid pairs and higher-order structures at the RNA-protein interface: analysis of the crystal structure database and a topological classification

水介导的核糖核苷酸-氨基酸对和RNA-蛋白质界面处的高级结构:晶体结构数据库分析和拓扑分类

Jangra, Raman; Trant, John F; Sharma, Purshotam

Biallelic Mutations in P4HTM Cause Syndromic Obesity

P4HTM基因的双等位基因突变导致综合征性肥胖

Saeed, Sadia; Ning, Lijiao; Badreddine, Alaa; Mirza, Muhammad Usman; Boissel, Mathilde; Khanam, Roohia; Manzoor, Jaida; Janjua, Qasim M; Khan, Waqas I; Toussaint, Bénédicte; Vaillant, Emmanuel; Amanzougarene, Souhila; Derhourhi, Mehdi; Trant, John F; Siegert, Anna-Maria; Lam, Brian Y H; Yeo, Giles S H; Chabraoui, Layachi; Touzani, Asmae; Kulkarni, Abhishek; Farooqi, I Sadaf; Bonnefond, Amélie; Arslan, Muhammad; Froguel, Philippe