日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Heterologous Fibrin Biopolymer as a Key Scaffold for Bone Regeneration: Synergistic Effects with Photobiomodulation and Membrane Therapy

异源纤维蛋白生物聚合物作为骨再生关键支架：与光生物调节和膜疗法的协同作用

期刊:Gels
影响因子:5.3
doi:10.3390/gels12010056
Moscatel, Matheus Bento Medeiros; Pagani, Bruna Trazzi; Trazzi, Beatriz Flávia de Moraes; Pascon, Tawana; Barraviera, Benedito; Ferreira Júnior, Rui Seabra; Buchaim, Daniela Vieira; Eleutério, Rachel Gomes; Buchaim, Rogerio Leone
发表日期：2026
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Endocannabinoid Enhancement via MAGL Inhibition in CDKL5 Deficiency: Selective Cellular Benefits and Domain-Specific Functional Effects in Adult Cdkl5 KO Mice

CDKL5 缺陷中通过 MAGL 抑制增强内源性大麻素：成年 Cdkl5 KO 小鼠的选择性细胞获益和结构域特异性功能效应

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27062773
Loi, Manuela; Mottolese, Nicola; Medici, Giorgio; Iannibelli, Feliciana; Interino, Nicolò; Candini, Giulia; Trebbi, Federica; Bove, Angelica Marina; Fiori, Jessica; Trazzi, Stefania; Ciani, Elisabetta
MAG
细胞生物学
发表日期：2026
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Safety and efficacy of Igk-TATk-CDKL5 gene therapy in mosaic CDKL5 deficiency

Igk-TATk-CDKL5基因疗法治疗嵌合型CDKL5缺陷的安全性和有效性

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1016/j.neurot.2025.e00727
Medici, Giorgio; Tassinari, Marianna; Loi, Manuela; Bove, Angelica Marina; Garofani, Beatrice Casadei; Volpedo, Greta; Mottolese, Nicola; Matteoli, Gabriele; Lo Martire, Viviana; Berteotti, Chiara; Candini, Giulia; Trebbi, Federica; Riva, Antonella; Striano, Pasquale; Zoccoli, Giovanna; Curia, Giulia; Trazzi, Stefania; Ciani, Elisabetta
发表日期：2025
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Lactic acid bacteria as microbial cell factories for the in vivo delivery of therapeutic proteins as secretable TAT fusion products

乳酸菌作为微生物细胞工厂，用于体内递送治疗性蛋白，以分泌型TAT融合产品的形式存在。

期刊:Journal of Biological Engineering
影响因子:6.5
doi:10.1186/s13036-025-00538-4
Medici, Giorgio; Candini, Giulia; Mottolese, Nicola; Uguagliati, Beatrice; Trebbi, Federica; Loi, Manuela; Bove, Angelica Marina; Stojanov, Spase; Esposito, Erika; Vitagliano, Rosalba; D'Amico, Federica; Turroni, Silvia; Fiori, Jessica; Berlec, Aleš; Trazzi, Stefania; Ciani, Elisabetta
微生物学
细胞生物学
发表日期：2025
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Adult-Onset Deletion of CDKL5 in Forebrain Glutamatergic Neurons Impairs Synaptic Integrity and Behavior in Mice

成年小鼠前脑谷氨酸能神经元中 CDKL5 基因缺失会损害突触完整性和行为

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26146626
Mottolese, Nicola; Iannibelli, Feliciana; Candini, Giulia; Trebbi, Federica; Loi, Manuela; Bove, Angelica Marina; Medici, Giorgio; Xiong, Zhi-Qi; Ciani, Elisabetta; Trazzi, Stefania
神经科学
发表日期：2025
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Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder

辅酶Q10在CDKL5缺乏症体外和体内模型中的有益抗氧化作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26052204
Loi, Manuela; Valenti, Francesca; Medici, Giorgio; Mottolese, Nicola; Candini, Giulia; Bove, Angelica Marina; Trebbi, Federica; Pincigher, Luca; Fato, Romana; Bergamini, Christian; Trazzi, Stefania; Ciani, Elisabetta
发表日期：2025
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A cross-correction gene therapy approach for CDKL5 deficiency disorder improves the pathological phenotype of CDD patient-derived cortical organoids

针对 CDKL5 缺乏症的交叉矫正基因治疗方法改善了 CDD 患者来源的皮质类器官的病理表型

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.8
doi:10.3389/fbioe.2025.1744903
Medici, Giorgio; Bove, Angelica M; Trazzi, Stefania; Puppo, Francesca; Loi, Manuela; Mottolese, Nicola; Candini, Giulia; Trebbi, Federica; Sanchez, Sandra; Muotri, Alysson R; Ciani, Elisabetta
3D/类器官
基因治疗
CDD
发表日期：2025
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Evaluation of Creatine Monohydrate Supplementation on the Gastrocnemius Muscle of Mice with Muscular Dystrophy: A Preliminary Study

肌酸一水合物补充剂对肌营养不良小鼠腓肠肌的影响评价：一项初步研究

期刊:Pathophysiology
影响因子:2.6
doi:10.3390/pathophysiology32010002
Fernandes, Victor Augusto Ramos; Dos Santos, Gabriela Pereira; Iatecola, Amilton; Buchaim, Daniela Vieira; Garcia, Ionaly Judith Faria; Reis, Carlos Henrique Bertoni; Bueno, Lívia Maluf Menegazzo; Pagani, Bruna Trazzi; Buchaim, Rogerio Leone; da Cunha, Marcelo Rodrigues
发表日期：2025
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Update on synthetic biomaterials combined with fibrin derivatives for regenerative medicine: Applications in bone defect treatment: Systematic review

合成生物材料与纤维蛋白衍生物联合应用于再生医学的最新进展：在骨缺损治疗中的应用：系统评价

期刊:World Journal of Orthopedics
影响因子:2.3
doi:10.5312/wjo.v16.i5.106181
Pagani, Bruna Trazzi; Rosso, Marcelie Priscila de Oliveira; Moscatel, Matheus Bento Medeiros; Trazzi, Beatriz Flavia de Moraes; da Cunha, Marcelo Rodrigues; Issa, João Paulo Mardegan; Buchaim, Daniela Vieira; Buchaim, Rogério Leone
发育与干细胞
发表日期：2025
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Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome

BKCa通道开放剂氯唑沙宗在脆性X综合征小鼠模型中的治疗效果

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/s41386-024-01956-6
Ferraguto, Celeste; Piquemal-Lagoueillat, Marion; Lemaire, Valerie; Moreau, Maïté M; Trazzi, Stefania; Uguagliati, Beatrice; Ciani, Elisabetta; Bertrand, Sandrine S; Louette, Eric; Bontempi, Bruno; Pietropaolo, Susanna
发表日期：2024
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