日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease

利用腺相关病毒介导的RNA干扰沉默突变亨廷顿蛋白可改善亨廷顿病YAC128小鼠模型的疾病症状。

Stanek, Lisa M; Sardi, Sergio P; Mastis, Bryan; Richards, Amy R; Treleaven, Christopher M; Taksir, Tatyana; Misra, Kuma; Cheng, Seng H; Shihabuddin, Lamya S

Gene transfer to the CNS is efficacious in immune-primed mice harboring physiologically relevant titers of anti-AAV antibodies

在体内含有生理相关滴度抗AAV抗体的免疫预激活小鼠中,基因转移到中枢神经系统是有效的。

Treleaven, Christopher M; Tamsett, Thomas J; Bu, Jie; Fidler, Jonathan A; Sardi, S Pablo; Hurlbut, Gregory D; Woodworth, Lisa A; Cheng, Seng H; Passini, Marco A; Shihabuddin, Lamya S; Dodge, James C

Disease progression in a mouse model of amyotrophic lateral sclerosis: the influence of chronic stress and corticosterone.

肌萎缩侧索硬化症小鼠模型中的疾病进展:慢性应激和皮质酮的影响

Fidler Jonathan A, Treleaven Christopher M, Frakes Ashley, Tamsett Thomas J, McCrate Mary, Cheng Seng H, Shihabuddin Lamya S, Kaspar Brian K, Dodge James C

Comparative analysis of acid sphingomyelinase distribution in the CNS of rats and mice following intracerebroventricular delivery

脑室内给药后大鼠和小鼠中枢神经系统酸性鞘磷脂酶分布的比较分析

Treleaven, Christopher M; Tamsett, Thomas; Fidler, Jonathan A; Taksir, Tatyana V; Cheng, Seng H; Shihabuddin, Lamya S; Dodge, James C

Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity

将AAV-IGF-1递送至中枢神经系统可通过调节异常的神经胶质细胞活性延长ALS小鼠的生存期。

Dodge, James C; Haidet, Amanda M; Yang, Wendy; Passini, Marco A; Hester, Mark; Clarke, Jennifer; Roskelley, Eric M; Treleaven, Christopher M; Rizo, Liza; Martin, Heather; Kim, Soo H; Kaspar, Rita; Taksir, Tatyana V; Griffiths, Denise A; Cheng, Seng H; Shihabuddin, Lamya S; Kaspar, Brian K