日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical trial of a MAP4K4 inhibitor to reduce infarct size in the pig: does cardioprotection in human stem cell-derived myocytes predict success in large mammals?

MAP4K4 抑制剂减少猪梗塞面积的临床前试验:人类干细胞衍生的心肌细胞中的心脏保护作用是否可以预示大型哺乳动物的成功?

Maaike Te Lintel Hekkert #, Gary Newton #, Kathryn Chapman, Rehan Aqil, Robert Downham, Robert Yan, Daphne Merkus, Gavin Whitlock, Charlotte A L Lane, Darren Cawkill, Trevor Perrior, Dirk J Duncker #, Michael D Schneider #

IKKε and TBK1 in diffuse large B-cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF-κB and IL-10 signalling

弥漫性大 B 细胞淋巴瘤中的 IKKε 和 TBK1:IKKε/TBK1 抑制剂抑制 NF-κB 和 IL-10 信号传导的可能作用机制

Matthew Carr, Sami Mamand, Kathryn L Chapman, Trevor Perrior, Simon D Wagner

Selective protection of human cardiomyocytes from anthracycline cardiotoxicity by small molecule inhibitors of MAP4K4

MAP4K4 小分子抑制剂选择性保护人类心肌细胞免受蒽环类药物心脏毒性

Pelin A Golforoush, Priyanka Narasimhan, Patricia P Chaves-Guerrero, Elsa Lawrence, Gary Newton, Robert Yan, Sian E Harding, Trevor Perrior, Kathryn L Chapman #, Michael D Schneider #

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

MAP4K4抑制可促进人干细胞衍生心肌细胞的存活并减少体内梗死面积

Lorna R Fiedler,Kathryn Chapman,Min Xie,Evie Maifoshie,Micaela Jenkins,Pelin Arabacilar Golforoush,Mohamed Bellahcene,Michela Noseda,Dörte Faust,Ashley Jarvis,Gary Newton,Marta Abreu Paiva,Mutsuo Harada,Daniel J Stuckey,Weihua Song,Josef Habib,Priyanka Narasimhan,Rehan Aqil,Devika Sanmugalingam,Robert Yan,Lorenzo Pavanello,Motoaki Sano,Sam C Wang,Robert D Sampson,Sunthar Kanayaganam,George E Taffet,Lloyd H Michael,Mark L Entman,Tse-Hua Tan,Sian E Harding,Caroline M R Low,Catherine Tralau-Stewart,Trevor Perrior,Michael D Schneider