日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

APRIL CAR 对多发性骨髓瘤患者的疗效有限,表明使用天然配体进行 CAR T 细胞治疗存在挑战

Lydia Lee, Wen Chean Lim, Daria Galas-Filipowicz, Kent Fung, Julia Taylor, Dominic Patel, Zulaikha Akbar, Elena Alvarez Mediavilla, Patrycja Wawrzyniecka, Debarati Shome, Rogier M Reijmers, Trillian Gregg, Leigh Wood, William Day, Virginie Cerec, Mathieu Ferrari, Simon Thomas, Shaun Cordoba, Shimobi

Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control

袖状胃切除术后胰岛素和肠促胰岛素分泌的时间可塑性以及胰岛素敏感性有助于血糖控制的持续改善。

Douros, Jonathan D; Niu, Jingjing; Sdao, Sophia; Gregg, Trillian; Merrins, Matthew J; Campbell, Jonathan; Tong, Jenny; D'Alessio, David

Sleeve gastrectomy rapidly enhances islet function independently of body weight

袖状胃切除术可迅速增强胰岛功能,且不受体重影响

Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Kelsey Fisher-Wellman, Manish Bharadwaj, Anthony Molina, Ramamani Arumugam, MacKenzie Martin, Enrico Petretto, Matthew J Merrins, Mark A Herman, Jenny Tong, Jonathan Campbell, David D'Alessio

Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells

肥胖依赖性 CDK1 信号刺激胰腺 β 细胞中复合物 I 的线粒体呼吸

Trillian Gregg, Sophia M Sdao, Rashpal S Dhillon, Jarred W Rensvold, Sophie L Lewandowski, David J Pagliarini, John M Denu, Matthew J Merrins

Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice

饮食诱导的肥胖小鼠胰岛素分泌的年龄依赖性保护

Elizabeth R De Leon, Jacqueline A Brinkman, Rachel J Fenske, Trillian Gregg, Brian A Schmidt, Dawn S Sherman, Nicole E Cummings, Darby C Peter, Michelle E Kimple, Dudley W Lamming, Matthew J Merrins

Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATP Channel Activity.

小鼠胰腺β细胞通过降低KATP通道活性来抵消与年龄相关的线粒体缺陷

Gregg Trillian, Poudel Chetan, Schmidt Brian A, Dhillon Rashpal S, Sdao Sophia M, Truchan Nathan A, Baar Emma L, Fernandez Luis A, Denu John M, Eliceiri Kevin W, Rogers Jeremy D, Kimple Michelle E, Lamming Dudley W, Merrins Matthew J

SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells

SORCS1 是代谢应激 β 细胞中正常胰岛素分泌颗粒生物合成所必需的

Melkam A Kebede, Angie T Oler, Trillian Gregg, Allison J Balloon, Adam Johnson, Kelly Mitok, Mary Rabaglia, Kathryn Schueler, Donald Stapleton, Candice Thorstenson, Lindsay Wrighton, Brendan J Floyd, Oliver Richards, Summer Raines, Kevin Eliceiri, Nabil G Seidah, Christopher Rhodes, Mark P Keller, J

Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion

Tomosyn-2 的磷酸化和降解解除了胰岛素分泌的抑制

Sushant Bhatnagar, Mufaddal S Soni, Lindsay S Wrighton, Alexander S Hebert, Amber S Zhou, Pradyut K Paul, Trillian Gregg, Mary E Rabaglia, Mark P Keller, Joshua J Coon, Alan D Attie