日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Baker-Gordon Syndrome-Associated Synaptotagmin-1 Mutations Reduce Synaptic Strength in Mouse Primary and Human-Induced Neuronal Culture Models

Baker-Gordon综合征相关突触结合蛋白-1突变降低小鼠原代和人诱导神经元培养模型中的突触强度

Fenske, Pascal; Hosseini, Hassan; Bouazza-Arostegui, Boris; Trimbuch, Thorsten; Herman, Melissa A; Rosenmund, Christian

The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

钠离子泄漏通道NALCN受神经元SNARE复合物蛋白的调控。

Usher, Samuel; Toulmé, Estelle; Florea, Roberta; Yatskevich, Stanislau; Jao, Christine C; Dijkhof, Luuk R H; Colding, Janne M; Joshi, Prajakta; Zilberleyb, Inna; Trimbuch, Thorsten; Brokowski, Bettina; Hauser, Alexander S; Leitner, Alexander; Rosenmund, Christian; Kschonsak, Marc; Pless, Stephan A

The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation.

氯离子细胞内通道 1 (CLIC1) 对小胶质细胞形态动力学和神经炎症至关重要。

Rifat Ali, Bickel Tom, Kreis Patricia, Trimbuch Thorsten, Onken Julia, Ivanov Andranik, Albertini Giulia, Beule Dieter, Mazzanti Michele, Singh Harpreet, Eickholt Britta J, De Strooper Bart, Geiger Jörg R P, Madry Christian

Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface.

神经递质的释放是由突触结合蛋白-1/SNARE复合物主要界面中钙诱导的重排触发的

Toulmé Estelle, Salazar Lázaro Andrea, Trimbuch Thorsten, Rizo Josep, Rosenmund Christian

The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A

突触小泡的启动池的稳定性和自发神经递质释放的钳制依赖于突触素-1A SNARE 结构域 C 端一半的完整性

Andrea Salazar Lázaro, Thorsten Trimbuch, Gülçin Vardar, Christian Rosenmund

Mutations of Single Residues in the Complexin N-terminus Exhibit Distinct Phenotypes in Synaptic Vesicle Fusion

复合物蛋白N端单个残基的突变在突触小泡融合中表现出不同的表型

Toulme, Estelle; Murach, Jacqueline; Bärfuss, Simon; Kroll, Jana; Malsam, Jörg; Trimbuch, Thorsten; Herman, Melissa A; Söllner, Thomas H; Rosenmund, Christian

Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface

神经递质的释放是由突触结合蛋白-1/SNARE复合物主要界面处钙离子诱导的重排触发的。

Toulmé, Estelle; Lázaro, Andrea Salazar; Trimbuch, Thorsten; Rizo, Josep; Rosenmund, Christian

Layer 1 of somatosensory cortex: an important site for input to a tiny cortical compartment

体感皮层第一层:向微小皮层区域输入信息的重要位置

Julia M T Ledderose, Timothy A Zolnik, Maria Toumazou, Thorsten Trimbuch, Christian Rosenmund, Britta J Eickholt, Dieter Jaeger, Matthew E Larkum, Robert N S Sachdev

Dynamin is primed at endocytic sites for ultrafast endocytosis

动力蛋白在内吞位点处于激活状态,可进行超快速内吞作用

Yuuta Imoto,Sumana Raychaudhuri,Ye Ma,Pascal Fenske,Eduardo Sandoval,Kie Itoh,Eva-Maria Blumrich,Hideaki T Matsubayashi,Lauren Mamer,Fereshteh Zarebidaki,Berit Söhl-Kielczynski,Thorsten Trimbuch,Shraddha Nayak,Janet H Iwasa,Jian Liu,Bin Wu,Taekjip Ha,Takanari Inoue,Erik M Jorgensen,Michael A Cousin,Christian Rosenmund,Shigeki Watanabe

The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms

脂质转运蛋白 ORP2 通过两种不同的机制调节突触神经递质的释放

Marion Weber-Boyvat, Jana Kroll, Thorsten Trimbuch, Vesa M Olkkonen, Christian Rosenmund