日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Baker-Gordon Syndrome-Associated Synaptotagmin-1 Mutations Reduce Synaptic Strength in Mouse Primary and Human-Induced Neuronal Culture Models

Baker-Gordon综合征相关突触结合蛋白-1突变降低小鼠原代和人诱导神经元培养模型中的突触强度

Fenske, Pascal; Hosseini, Hassan; Bouazza-Arostegui, Boris; Trimbuch, Thorsten; Herman, Melissa A; Rosenmund, Christian

The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

钠离子泄漏通道NALCN受神经元SNARE复合物蛋白的调控。

Usher, Samuel; Toulmé, Estelle; Florea, Roberta; Yatskevich, Stanislau; Jao, Christine C; Dijkhof, Luuk R H; Colding, Janne M; Joshi, Prajakta; Zilberleyb, Inna; Trimbuch, Thorsten; Brokowski, Bettina; Hauser, Alexander S; Leitner, Alexander; Rosenmund, Christian; Kschonsak, Marc; Pless, Stephan A

The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation.

氯离子细胞内通道 1 (CLIC1) 对小胶质细胞形态动力学和神经炎症至关重要。

Rifat Ali, Bickel Tom, Kreis Patricia, Trimbuch Thorsten, Onken Julia, Ivanov Andranik, Albertini Giulia, Beule Dieter, Mazzanti Michele, Singh Harpreet, Eickholt Britta J, De Strooper Bart, Geiger Jörg R P, Madry Christian

Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface.

神经递质的释放是由突触结合蛋白-1/SNARE复合物主要界面中钙诱导的重排触发的

Toulmé Estelle, Salazar Lázaro Andrea, Trimbuch Thorsten, Rizo Josep, Rosenmund Christian

Mutations of Single Residues in the Complexin N-terminus Exhibit Distinct Phenotypes in Synaptic Vesicle Fusion

复合物蛋白N端单个残基的突变在突触小泡融合中表现出不同的表型

Toulme, Estelle; Murach, Jacqueline; Bärfuss, Simon; Kroll, Jana; Malsam, Jörg; Trimbuch, Thorsten; Herman, Melissa A; Söllner, Thomas H; Rosenmund, Christian

Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface

神经递质的释放是由突触结合蛋白-1/SNARE复合物主要界面处钙离子诱导的重排触发的。

Toulmé, Estelle; Lázaro, Andrea Salazar; Trimbuch, Thorsten; Rizo, Josep; Rosenmund, Christian

Synaptotagmin-1 drives synchronous Ca(2+)-triggered fusion by C(2)B-domain-mediated synaptic-vesicle-membrane attachment

突触结合蛋白-1通过C(2)B结构域介导的突触小泡-膜连接,驱动同步的Ca(2+)触发融合。

Chang, Shuwen; Trimbuch, Thorsten; Rosenmund, Christian

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C(1)C(2)BMUN.

从 Munc13-1 C(1)C(2)BMUN 的晶体结构中对神经递质释放和突触前可塑性的机制性见解

Xu Junjie, Camacho Marcial, Xu Yibin, Esser Victoria, Liu Xiaoxia, Trimbuch Thorsten, Pan Yun-Zu, Ma Cong, Tomchick Diana R, Rosenmund Christian, Rizo Josep

Distinct Localization of SNAP47 Protein in GABAergic and Glutamatergic Neurons in the Mouse and the Rat Hippocampus

SNAP47蛋白在小鼠和大鼠海马GABA能神经元和谷氨酸能神经元中的不同定位

Münster-Wandowski, Agnieszka; Heilmann, Heike; Bolduan, Felix; Trimbuch, Thorsten; Yanagawa, Yuchio; Vida, Imre

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

精确的体感拓扑丘脑皮质轴突导向依赖于LPA介导的PRG-2/Radixin信号通路

Cheng, Jin; Sahani, Sadhna; Hausrat, Torben Johann; Yang, Jenq-Wei; Ji, Haichao; Schmarowski, Nikolai; Endle, Heiko; Liu, Xinfeng; Li, Yunbo; Böttche, Rahel; Radyushkin, Konstantin; Maric, Hans M; Hoerder-Suabedissen, Anna; Molnár, Zoltán; Prouvot, Pierre-Hugues; Trimbuch, Thorsten; Ninnemann, Olaf; Huai, Jisen; Fan, Wei; Visentin, Barbara; Sabbadini, Roger; Strømgaard, Kristian; Stroh, Albrecht; Luhmann, Heiko J; Kneussel, Matthias; Nitsch, Robert; Vogt, Johannes